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Department of Biomedical Engineering
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Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2021 | Pubmed ID: 33758095
The Role of Mechanically-Activated Ion Channels Piezo1, Piezo2, and TRPV4 in Chondrocyte Mechanotransduction and Mechano-Therapeutics for Osteoarthritis.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35602590
Hydrogel Swelling-Mediated Strain Induces Cell Alignment at Dentin Interfaces.
ACS biomaterials science & engineering Aug, 2022 | Pubmed ID: 35793542
Effect of knee joint loading on chondrocyte mechano-vulnerability and severity of post-traumatic osteoarthritis induced by ACL-injury in mice.
Osteoarthritis and cartilage open Mar, 2022 | Pubmed ID: 36474470
PIEZO1 is downregulated in glenohumeral chondrocytes in early cuff tear arthropathy following a massive rotator cuff tear in a mouse model.
Frontiers in bioengineering and biotechnology , 2023 | Pubmed ID: 37731766
University of Rochester
University of Rochester Medical Center
Brian C. Wise1,2,
Keshia E. Mora1,2,
Whasil Lee1,2,3,
Mark R. Buckley1,2
1Department of Biomedical Engineering, University of Rochester,
2Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center,
3Department of Pharmacology and Physiology, University of Rochester Medical Center
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