UBC Centre for Heart Lung Innovation
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Biomarkers in airway diseases.
Canadian respiratory journal , 2013 | Pubmed ID: 23762888
COPD in never smokers: prognosis unveiled.
The Lancet. Respiratory medicine Sep, 2013 | Pubmed ID: 24461602
Smoke and mirrors: the perils of water-pipe smoking and implications for Western countries.
Chest Oct, 2014 | Pubmed ID: 25287994
A sum greater than its parts.
The European respiratory journal Dec, 2014 | Pubmed ID: 25435523
COPD exacerbations: reducing the burden by predicting the future?
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Dec, 2014 | Pubmed ID: 25517799
Plasma pro-surfactant protein B and lung function decline in smokers.
The European respiratory journal Apr, 2015 | Pubmed ID: 25614175
Absolute leukocyte telomere length in HIV-infected and uninfected individuals: evidence of accelerated cell senescence in HIV-associated chronic obstructive pulmonary disease.
PloS one , 2015 | Pubmed ID: 25885433
Empowering family physicians to impart proper inhaler teaching to patients with chronic obstructive pulmonary disease and asthma.
Canadian respiratory journal , 2015 | Pubmed ID: 26436910
Chronic Obstructive Pulmonary Disease and Stroke. Strange Bedfellows.
American journal of respiratory and critical care medicine Feb, 2016 | Pubmed ID: 26829416
What is asthma-COPD overlap syndrome? Towards a consensus definition from a round table discussion.
The European respiratory journal Sep, 2016 | Pubmed ID: 27338195
Airway hyperresponsiveness in chronic obstructive pulmonary disease: A marker of asthma-chronic obstructive pulmonary disease overlap syndrome?
The Journal of allergy and clinical immunology Dec, 2016 | Pubmed ID: 27345171
A Systematic Review of Diagnostic Biomarkers of COPD Exacerbation.
PloS one , 2016 | Pubmed ID: 27434033
COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry.
PloS one , 2016 | Pubmed ID: 27525416
The bronchial epithelial cell bacterial microbiome and host response in patients infected with human immunodeficiency virus.
BMC pulmonary medicine Nov, 2016 | Pubmed ID: 27829448
Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection.
PloS one , 2016 | Pubmed ID: 27902753
Longitudinal study of surrogate aging measures during human immunodeficiency virus seroconversion.
Aging Feb, 2017 | Pubmed ID: 28237978
The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD.
Respirology (Carlton, Vic.) May, 2017 | Pubmed ID: 28342288
Serum IgG and risk of exacerbations and hospitalizations in chronic obstructive pulmonary disease.
The Journal of allergy and clinical immunology Oct, 2017 | Pubmed ID: 28456620
Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease.
EBioMedicine May, 2017 | Pubmed ID: 28461224
Concern of underdiagnosing asthma-COPD overlap syndrome if age limit of 40 years for asthma is used.
The European respiratory journal Aug, 2017 | Pubmed ID: 28775052
Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets.
BMJ (Clinical research ed.) Sep, 2017 | Pubmed ID: 28947632
Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD.
Respiratory research Feb, 2018 | Pubmed ID: 29444682
Decreased telomere length in the small airway epithelium suggests accelerated aging in the lungs of persons living with human immunodeficiency virus (HIV).
Respiratory research Jun, 2018 | Pubmed ID: 29895291
Relationship of Absolute Telomere Length With Quality of Life, Exacerbations, and Mortality in COPD.
Chest Aug, 2018 | Pubmed ID: 30017346
Decreased microbiome diversity in the HIV small airway epithelium.
Respiratory research Jul, 2018 | Pubmed ID: 30053882
Sputum Microbiome Is Associated with 1-Year Mortality after Chronic Obstructive Pulmonary Disease Hospitalizations.
American journal of respiratory and critical care medicine May, 2019 | Pubmed ID: 30376356
Inhaled corticosteroids in COPD: the final verdict is….
The European respiratory journal Dec, 2018 | Pubmed ID: 30545961
Introduction to precision medicine in COPD.
The European respiratory journal Apr, 2019 | Pubmed ID: 30679189
The Safety and Efficacy of Marijuana in Persons Living with HIV.
AIDS reviews , 2019 | Pubmed ID: 31332397
Effects of sex and chronic cigarette smoke exposure on the mouse cecal microbiome.
PloS one , 2020 | Pubmed ID: 32251484
ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19.
The European respiratory journal May, 2020 | Pubmed ID: 32269089
COVID-19 and nicotine as a mediator of ACE-2.
The European respiratory journal Jun, 2020 | Pubmed ID: 32350104
Reply to: "Current smoking is not associated with COVID-19".
The European respiratory journal Jun, 2020 | Pubmed ID: 32366490
Smoking, ACE-2 and COVID-19: ongoing controversies.
The European respiratory journal Jul, 2020 | Pubmed ID: 32430431
Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-analysis.
Chest Oct, 2020 | Pubmed ID: 32439504
COVID-19 and COPD.
The European respiratory journal Aug, 2020 | Pubmed ID: 32817205
Abundance of Non-Polarized Lung Macrophages with Poor Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD).
Biomedicines Oct, 2020 | Pubmed ID: 33050042
DNA methylation is associated with airflow obstruction in patients living with HIV.
Thorax May, 2021 | Pubmed ID: 33443234
Olodaterol exerts anti-inflammatory effects on COPD airway epithelial cells.
Respiratory research Feb, 2021 | Pubmed ID: 33622325
Inhaled corticosteroids downregulate SARS-CoV-2-related genes in COPD: results from a randomised controlled trial.
The European respiratory journal Jul, 2021 | Pubmed ID: 33795322
Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures.
Scientific reports Apr, 2021 | Pubmed ID: 33859282
IgG Levels and Mortality in Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine Aug, 2021 | Pubmed ID: 33945775
Effects of Inhaled Corticosteroid/Long-Acting β-Agonist Combination on the Airway Microbiome of Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Clinical Trial (DISARM).
American journal of respiratory and critical care medicine Nov, 2021 | Pubmed ID: 34464242
Epigenetic blood biomarkers of ageing and mortality in COPD.
The European respiratory journal Dec, 2021 | Pubmed ID: 34561282
Epigenetic marker of telomeric age is associated with exacerbations and hospitalizations in chronic obstructive pulmonary disease.
Respiratory research Dec, 2021 | Pubmed ID: 34937547
Distinct bronchial microbiome precedes clinical diagnosis of lung cancer.
Molecular cancer Mar, 2022 | Pubmed ID: 35255902
Airway Aging and Methylation Disruptions in HIV-associated Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine Jul, 2022 | Pubmed ID: 35426765
Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis.
American journal of respiratory and critical care medicine Aug, 2022 | Pubmed ID: 35536696
Inhaled Corticosteroids Selectively Alter the Microbiome and Host Transcriptome in the Small Airways of Patients with Chronic Obstructive Pulmonary Disease.
Biomedicines May, 2022 | Pubmed ID: 35625847
The impact of IgG subclass deficiency on the risk of mortality in hospitalized patients with COPD.
Respiratory research May, 2022 | Pubmed ID: 35641962
Airway Eosinophilia on Bronchoalveolar Lavage and the Risk of Exacerbations in COPD.
Biomedicines Jun, 2022 | Pubmed ID: 35740433
The relationship between the epigenetic aging biomarker "grimage" and lung function in both the airway and blood of people living with HIV: An observational cohort study.
EBioMedicine Sep, 2022 | Pubmed ID: 35944348
Exposure to diesel exhaust alters the functional metagenomic composition of the airway microbiome in former smokers.
Environmental research Jan, 2023 | Pubmed ID: 36403657
Common Respiratory Pathogens Other Than in Small Airways are Associated With Neutrophilic Inflammation and Poor Health Status in Stable COPD Patients.
Chronic obstructive pulmonary diseases (Miami, Fla.) Jan, 2023 | Pubmed ID: 36459695
The Blood DNA Methylation Clock GrimAge Is a Robust Surrogate for Airway Epithelia Aging.
Biomedicines Dec, 2022 | Pubmed ID: 36551848
Systemic and Airway Epigenetic Disruptions Are Associated with Health Status in COPD.
Biomedicines Jan, 2023 | Pubmed ID: 36672643
HIV and chronic lung disease.
Current opinion in HIV and AIDS Mar, 2023 | Pubmed ID: 36722198
Characterization of the Lower Airways and Oral Microbiota in Healthy Young Persons in the Community.
Biomedicines Mar, 2023 | Pubmed ID: 36979819
Microbial dysbiosis and the host airway epithelial response: insights into HIV-associated COPD using multi'omics profiling.
Respiratory research May, 2023 | Pubmed ID: 37143066
Methionine-producing tumor micro(be) environment fuels growth of solid tumors.
Cellular oncology (Dordrecht) Dec, 2023 | Pubmed ID: 37318751
Predicting steroid responsiveness using airway smooth muscle in COPD: a HISTORIC study.
The European respiratory journal Jul, 2023 | Pubmed ID: 37474151
Airway Epithelial-Derived Immune Mediators in COVID-19.
Viruses Jul, 2023 | Pubmed ID: 37631998
Single-cell RNA sequencing of bronchoscopy specimens: development of a rapid minimal handling protocol.
BioTechniques Oct, 2023 | Pubmed ID: 37815826
Cluster Analysis to Identify Long COVID Phenotypes Using Xe Magnetic Resonance Imaging: A Multi-centre Evaluation.
The European respiratory journal Feb, 2024 | Pubmed ID: 38331459
Rachel L Eddy1,2,
George H Xu3,
Jonathon A Leipsic1,4,
Janice M Leung1,2,
Don D Sin1,2,
Chase S Hall5,
Roger C Tam3,4
1UBC Centre for Heart Lung Innovation, St. Paul’s Hospital,
2Division of Respiratory Medicine, Department of Medicine, University of British Columbia,
3School of Biomedical Engineering, University of British Columbia,
4Department of Radiology, University of British Columbia,
5Division of Pulmonary and Critical Care Medicine, University of Kansas Medical Center
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