Shernaz X Bamji

Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.

Cadherins: actin with the cytoskeleton to form synapses.

BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-beta-catenin interactions.

ErbB4-neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms.

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2, and beta-catenin.

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses.

Semaphorin 5B mediates synapse elimination in hippocampal neurons.

Progranulin deficiency leads to enhanced cell vulnerability and TDP-43 translocation in primary neuronal cultures.

N-cadherin and neuroligins cooperate to regulate synapse formation in hippocampal cultures.

Cadherin-catenin adhesion complexes at the synapse.

Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na⁺/H⁺ exchanger NHE5.

Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses.

β-Pix modulates actin-mediated recruitment of synaptic vesicles to synapses.

Hyperinsulinemia drives diet-induced obesity independently of brain insulin production.