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Department of Chemical Engineering
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Computational and experimental analysis of DNA shuffling.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2003 | Pubmed ID: 12626764
PEG conjugation moderately protects adeno-associated viral vectors against antibody neutralization.
Biotechnology and bioengineering Oct, 2005 | Pubmed ID: 15937953
Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.
Nature biotechnology Feb, 2006 | Pubmed ID: 16429148
Noise in protein expression scales with natural protein abundance.
Nature genetics Jun, 2006 | Pubmed ID: 16715097
Construction of diverse adeno-associated viral libraries for directed evolution of enhanced gene delivery vehicles.
Nature protocols , 2006 | Pubmed ID: 17406299
Living with noisy genes: how cells function reliably with inherent variability in gene expression.
Annual review of biophysics and biomolecular structure , 2007 | Pubmed ID: 17477840
Gene expression: dialing up the frequency.
Current biology : CB Dec, 2008 | Pubmed ID: 19108770
Epigenetic and conventional regulation is distributed among activators of FLO11 allowing tuning of population-level heterogeneity in its expression.
PLoS genetics Oct, 2009 | Pubmed ID: 19798446
Noise can induce bimodality in positive transcriptional feedback loops without bistability.
Science (New York, N.Y.) Feb, 2010 | Pubmed ID: 20185727
Detection of single-molecule H2O2 signalling from epidermal growth factor receptor using fluorescent single-walled carbon nanotubes.
Nature nanotechnology Apr, 2010 | Pubmed ID: 20208549
A regulatory role for repeated decoy transcription factor binding sites in target gene expression.
Molecular systems biology , 2012 | Pubmed ID: 22453733
Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM.
Nucleic acids research May, 2013 | Pubmed ID: 23470991
Using the Cre-lox System to Randomize Target Gene Expression States and Generate Diverse Phenotypes.
Biotechnology and bioengineering Jun, 2013 | Pubmed ID: 23733452
Massachusetts Institute of Technology
Christopher J. Zopf1,
Narendra Maheshri1
1Department of Chemical Engineering, Massachusetts Institute of Technology
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