Department of Molecular Biology & Microbiology
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Expression of the receptor protein-tyrosine phosphatase, PTPmu, restores E-cadherin-dependent adhesion in human prostate carcinoma cells.
The Journal of biological chemistry Mar, 2002 | Pubmed ID: 11801604
Protein kinase C delta (PKCdelta) is required for protein tyrosine phosphatase mu (PTPmu)-dependent neurite outgrowth.
Molecular and cellular neurosciences Feb, 2002 | Pubmed ID: 11860281
Protein tyrosine phosphatase-mu differentially regulates neurite outgrowth of nasal and temporal neurons in the retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2002 | Pubmed ID: 11978837
PTP mu-dependent growth cone rearrangement is regulated by Cdc42.
Journal of neurobiology Sep, 2003 | Pubmed ID: 12884260
The receptor protein tyrosine phosphatase mu, PTPmu, regulates histogenesis of the chick retina.
Developmental biology Dec, 2003 | Pubmed ID: 14623235
alpha3beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPmu expression and cell-cell adhesion.
The Journal of cell biology Dec, 2003 | Pubmed ID: 14691142
PTPmu signaling via PKCdelta is instructive for retinal ganglion cell guidance.
Molecular and cellular neurosciences Apr, 2004 | Pubmed ID: 15080886
Modulation of Rho GTPase activity alleviates chondroitin sulfate proteoglycan-dependent inhibition of neurite extension.
Journal of neuroscience research Jul, 2004 | Pubmed ID: 15211597
Receptor protein tyrosine phosphatases regulate neural development and axon guidance.
Developmental biology Nov, 2004 | Pubmed ID: 15464569
PTP mu expression and catalytic activity are required for PTP mu-mediated neurite outgrowth and repulsion.
Molecular and cellular neurosciences Jan, 2005 | Pubmed ID: 15607952
The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1.
The Journal of biological chemistry Feb, 2006 | Pubmed ID: 16380380
Protein-tyrosine phosphatase (PTP) wedge domain peptides: a novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase function.
The Journal of biological chemistry Jun, 2006 | Pubmed ID: 16613844
Rho GTPases regulate PTPmu-mediated nasal neurite outgrowth and temporal repulsion of retinal ganglion cell neurons.
Molecular and cellular neurosciences Mar, 2007 | Pubmed ID: 17234431
E-cadherin promotes retinal ganglion cell neurite outgrowth in a protein tyrosine phosphatase-mu-dependent manner.
Molecular and cellular neurosciences Mar, 2007 | Pubmed ID: 17276081
Tumor-derived extracellular mutations of PTPRT /PTPrho are defective in cell adhesion.
Molecular cancer research : MCR Jul, 2008 | Pubmed ID: 18644975
BCCIP associates with the receptor protein tyrosine phosphatase PTPmu.
Journal of cellular biochemistry Nov, 2008 | Pubmed ID: 18773424
PTPmu suppresses glioma cell migration and dispersal.
Neuro-oncology Dec, 2009 | Pubmed ID: 19304959
Proteolytic cleavage of protein tyrosine phosphatase mu regulates glioblastoma cell migration.
Cancer research Sep, 2009 | Pubmed ID: 19690139
Novel peptide mimetic small molecules of the HAV motif in N-cadherin inhibit N-cadherin-mediated neurite outgrowth and cell adhesion.
Peptides Dec, 2009 | Pubmed ID: 19765627
Stimulation of N-cadherin-dependent neurite outgrowth by small molecule peptide mimetic agonists of the N-cadherin HAV motif.
Peptides May, 2010 | Pubmed ID: 20153391
Distinct PTPmu-associated signaling molecules differentially regulate neurite outgrowth on E-, N-, and R-cadherin.
Molecular and cellular neurosciences May, 2010 | Pubmed ID: 20197094
Cancer-derived mutations in the fibronectin III repeats of PTPRT/PTPrho inhibit cell-cell aggregation.
Cell communication & adhesion Dec, 2009 | Pubmed ID: 20230342
A novel molecular diagnostic of glioblastomas: detection of an extracellular fragment of protein tyrosine phosphatase mu.
Neoplasia (New York, N.Y.) Apr, 2010 | Pubmed ID: 20360941
Identification of phospholipase C gamma1 as a protein tyrosine phosphatase mu substrate that regulates cell migration.
Journal of cellular biochemistry Jan, 2011 | Pubmed ID: 20506511
Characterization of the adhesive properties of the type IIb subfamily receptor protein tyrosine phosphatases.
Cell communication & adhesion Apr, 2010 | Pubmed ID: 20521994
Cancer cells cut homophilic cell adhesion molecules and run.
Cancer research Jan, 2011 | Pubmed ID: 21084269
Tumor-derived extracellular fragments of receptor protein tyrosine phosphatases (RPTPs) as cancer molecular diagnostic tools.
Anti-cancer agents in medicinal chemistry Jan, 2011 | Pubmed ID: 21235433
Sustained delivery of activated Rho GTPases and BDNF promotes axon growth in CSPG-rich regions following spinal cord injury.
PloS one , 2011 | Pubmed ID: 21283639
Should I stay or should I go? Shedding of RPTPs in cancer cells switches signals from stabilizing cell-cell adhesion to driving cell migration.
Cell adhesion & migration Jul-Aug, 2011 | Pubmed ID: 21785275
Novel cryo-imaging of the glioma tumor microenvironment reveals migration and dispersal pathways in vivid three-dimensional detail.
Cancer research Sep, 2011 | Pubmed ID: 21862632
Cryo-image Analysis of Tumor Cell Migration, Invasion, and Dispersal in a Mouse Xenograft Model of Human Glioblastoma Multiforme.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Nov, 2011 | Pubmed ID: 22125093
MR molecular imaging of prostate cancer with a peptide-targeted contrast agent in a mouse orthotopic prostate cancer model.
Pharmaceutical research Apr, 2012 | Pubmed ID: 22139536
Cadherin-11, a marker of the mesenchymal phenotype, regulates glioblastoma cell migration and survival in vivo.
Molecular cancer research : MCR Mar, 2012 | Pubmed ID: 22267545
Protein tyrosine phosphatase mu regulates glioblastoma cell growth and survival in vivo.
Neuro-oncology May, 2012 | Pubmed ID: 22505657
Synthesis and evaluation of a peptide targeted small molecular Gd-DOTA monoamide conjugate for MR molecular imaging of prostate cancer.
Bioconjugate chemistry Aug, 2012 | Pubmed ID: 22812444
Mapping the mechanome of live stem cells using a novel method to measure local strain fields in situ at the fluid-cell interface.
PloS one , 2012 | Pubmed ID: 22970134
Molecular mechanisms of cancer cell-cell interactions: cell-cell adhesion-dependent signaling in the tumor microenvironment.
Cell adhesion & migration Jul-Aug, 2012 | Pubmed ID: 22983192
Single cell molecular recognition of migrating and invading tumor cells using a targeted fluorescent probe to receptor PTPmu.
International journal of cancer. Journal international du cancer Apr, 2013 | Pubmed ID: 22987116
Synthesis and Evaluation of a Targeted Nanoglobular Dual-Modal Imaging Agent for MR Imaging and Image-Guided Surgery of Prostate Cancer.
Pharmaceutical research Mar, 2013 | Pubmed ID: 23471641
Molecular Magnetic Resonance Imaging of Tumors with a PTPµ Targeted Contrast Agent.
Translational oncology Jun, 2013 | Pubmed ID: 23730413
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