Departments of Paediatrics and Clinical Neurosciences,
Alberta Children's Hospital Research Institute,
Departments of Paediatrics and Clinical Neurosciences, Alberta Children's Hospital Research Institute
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Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo.
Epilepsia Apr, 2002 | Pubmed ID: 11952765
Ictal EEG patterns in band heterotopia.
Epilepsia Apr, 2002 | Pubmed ID: 11952771
Clinical and electrographic features of epileptic spasms persisting beyond the second year of life.
Epilepsia Jun, 2002 | Pubmed ID: 12060022
Age-dependent differences in flurothyl-induced c-fos and c-jun mRNA expression in the mouse brain.
Developmental neuroscience , 2002 | Pubmed ID: 12457067
Molecular biology and ontogeny of gamma-aminobutyric acid (GABA) receptors in the mammalian central nervous system.
Journal of child neurology Jan, 2003 | Pubmed ID: 12661937
Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo.
Epilepsia Jun, 2003 | Pubmed ID: 12790887
Intravenous immunoglobulin as adjunctive therapy for juvenile spasms.
Journal of child neurology Jun, 2003 | Pubmed ID: 12886970
Voltage-dependent block of N-methyl-D-aspartate receptors by the novel anticonvulsant dibenzylamine, a bioactive constituent of L-(+)-beta-hydroxybutyrate.
Epilepsia Oct, 2003 | Pubmed ID: 14510820
The ketogenic diet increases mitochondrial uncoupling protein levels and activity.
Annals of neurology Apr, 2004 | Pubmed ID: 15048898
Molecular biology and ontogeny of glutamate receptors in the mammalian central nervous system.
Journal of child neurology May, 2004 | Pubmed ID: 15224708
Basic science behind the catastrophic epilepsies.
Epilepsia , 2004 | Pubmed ID: 15283705
A cDNA microarray analysis of gene expression profiles in rat hippocampus following a ketogenic diet.
Brain research. Molecular brain research Oct, 2004 | Pubmed ID: 15469884
Lack of long-term histopathologic changes in brain and skeletal muscle of mice treated with a ketogenic diet.
Journal of child neurology Jul, 2004 | Pubmed ID: 15526964
Clinical experience with zonisamide monotherapy and adjunctive therapy in children with epilepsy at a tertiary care referral center.
Journal of child neurology Mar, 2005 | Pubmed ID: 15832611
Electrophysiological properties of human hypothalamic hamartomas.
Annals of neurology Sep, 2005 | Pubmed ID: 16130091
Impaired motor control in patients with benign focal epilepsy of childhood.
Journal of child neurology Feb, 2006 | Pubmed ID: 16566883
Anticonvulsant mechanisms of the ketogenic diet.
Epilepsia Jan, 2007 | Pubmed ID: 17241207
Ketone bodies are protective against oxidative stress in neocortical neurons.
Journal of neurochemistry Jun, 2007 | Pubmed ID: 17403035
Electrophysiological properties and subunit composition of GABAA receptors in patients with gelastic seizures and hypothalamic hamartoma.
Journal of neurophysiology Jul, 2007 | Pubmed ID: 17428906
The ketogenic diet: stoking the powerhouse of the cell.
Epilepsy currents / American Epilepsy Society Mar-Apr, 2007 | Pubmed ID: 17505556
Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis.
Seminars in pediatric neurology Jun, 2007 | Pubmed ID: 17544947
Do seizures affect the developing brain? Lessons from the laboratory.
Journal of child neurology May, 2007 | Pubmed ID: 17690084
Substantia(ting) ketone body effects on neuronal excitability.
Epilepsy currents / American Epilepsy Society Sep-Oct, 2007 | Pubmed ID: 17998978
GABAA receptor-mediated activation of L-type calcium channels induces neuronal excitation in surgically resected human hypothalamic hamartomas.
Epilepsia May, 2008 | Pubmed ID: 18076645
Fasting is neuroprotective following traumatic brain injury.
Journal of neuroscience research Jun, 2008 | Pubmed ID: 18241053
The ketogenic diet and epilepsy.
Current opinion in clinical nutrition and metabolic care Mar, 2008 | Pubmed ID: 18301085
Can reducing sugar retard kindling?
Epilepsy currents / American Epilepsy Society May-Jun, 2008 | Pubmed ID: 18488064
Oxidative impairment of hippocampal long-term potentiation involves activation of protein phosphatase 2A and is prevented by ketone bodies.
Journal of neuroscience research Nov, 2008 | Pubmed ID: 18646208
GABA(A) receptor-mediated excitation in dissociated neurons from human hypothalamic hamartomas.
Experimental neurology Oct, 2008 | Pubmed ID: 18675803
Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group.
Epilepsia Feb, 2009 | Pubmed ID: 18823325
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies.
Brain research reviews Mar, 2009 | Pubmed ID: 18845187
Bicarbonate contributes to GABAA receptor-mediated neuronal excitation in surgically resected human hypothalamic hamartomas.
Epilepsy research Jan, 2009 | Pubmed ID: 19022626
Epilepsia. Ketogenic diet and treatments. Introduction/perspectives.
Epilepsia Nov, 2008 | Pubmed ID: 19049573
UCP-mediated free fatty acid uncoupling of isolated cortical mitochondria from fasted animals: correlations to dietary modulations.
Epilepsia Nov, 2008 | Pubmed ID: 19049607
The ketogenic diet in a pill: is this possible?
Epilepsia Nov, 2008 | Pubmed ID: 19049610
Ketogenic diets: evidence for short- and long-term efficacy.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics Apr, 2009 | Pubmed ID: 19332337
Arresting a seizure by dropping a little Acid.
Epilepsy currents / American Epilepsy Society Mar-Apr, 2009 | Pubmed ID: 19421382
Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1-null mice.
Epilepsia Sep, 2009 | Pubmed ID: 19490051
Reversible lamotrigine-induced neurobehavioral disturbances in children with epilepsy.
Journal of child neurology Feb, 2010 | Pubmed ID: 19494356
Ketogenic diets: an update for child neurologists.
Journal of child neurology Aug, 2009 | Pubmed ID: 19535814
Anticonvulsant effects of the selective melatonin receptor agonist ramelteon.
Epilepsy & behavior : E&B Sep, 2009 | Pubmed ID: 19682955
Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors.
Journal of neurochemistry Jul, 2010 | Pubmed ID: 20374433
A "happy" toddler presenting with sudden, life-threatening seizures.
Seminars in pediatric neurology Mar, 2010 | Pubmed ID: 20434691
The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma.
Nutrition & metabolism , 2010 | Pubmed ID: 20831808
Another Look at Early GABAergic Neurotransmission: Maybe It's Not So Exciting After All!
Epilepsy currents / American Epilepsy Society Sep, 2010 | Pubmed ID: 20944825
How does altered metabolism lead to seizure control? Partially filling the knowledge gap.
Epilepsy currents / American Epilepsy Society Nov, 2010 | Pubmed ID: 21157545
Pediatric neuropharmacotherapeutics. Introduction.
Seminars in pediatric neurology Dec, 2010 | Pubmed ID: 21183125
L-Type calcium channel blockade reduces network activity in human epileptic hypothalamic hamartoma tissue.
Epilepsia Mar, 2011 | Pubmed ID: 21269296
Pediatric stroke.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Sep, 2011 | Pubmed ID: 21336993
Ketogenic diet in the treatment of seizures associated with hypothalamic hamartomas.
Epilepsy research May, 2011 | Pubmed ID: 21377333
The ketogenic diet: what has science taught us?
Epilepsy research Jul, 2012 | Pubmed ID: 21856126
Adenosine: a fundamental factor formed from Fatty feasts for fighting fits?
Epilepsy currents / American Epilepsy Society Jan, 2012 | Pubmed ID: 22368522
The ketogenic diet as a treatment paradigm for diverse neurological disorders.
Frontiers in pharmacology , 2012 | Pubmed ID: 22509165
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
PloS one , 2012 | Pubmed ID: 22563484
Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis.
PloS one , 2012 | Pubmed ID: 22567104
Finding a better drug for epilepsy: antiepileptogenesis targets.
Epilepsia Nov, 2012 | Pubmed ID: 23061663
Sweets Are BAD for Seizures.
Epilepsy currents / American Epilepsy Society Nov, 2012 | Pubmed ID: 23447715
Unilateral Foot Drop as an Initial Presentation of a Brain Tumor in a Child.
Journal of child neurology Mar, 2013 | Pubmed ID: 23456535
Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices.
Neurobiology of disease Jun, 2013 | Pubmed ID: 23466697
High dose folic acid supplementation of rats alters synaptic transmission and seizure susceptibility in offspring.
Scientific reports , 2013 | Pubmed ID: 23492951
Ketogenic diet improves core symptoms of autism in BTBR mice.
PloS one , 2013 | Pubmed ID: 23755170
Ketogenic Diets, Mitochondria and Neurological Diseases.
Journal of lipid research May, 2014 | Pubmed ID: 24847102
Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels.
Molecular brain , 2014 | Pubmed ID: 24886461
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