Institut für Zelluläre und Molekulare Physiologie
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Plasmin in nephrotic urine activates the epithelial sodium channel.
Journal of the American Society of Nephrology : JASN Feb, 2009 | Pubmed ID: 19073825
The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation.
The Journal of biological chemistry Oct, 2009 | Pubmed ID: 19717556
Cholesterol depletion of the plasma membrane prevents activation of the epithelial sodium channel (ENaC) by SGK1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology , 2009 | Pubmed ID: 19910701
Functional characterization of a partial loss-of-function mutation of the epithelial sodium channel (ENaC) associated with atypical cystic fibrosis.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology , 2010 | Pubmed ID: 20054153
Atomic force microscopy reveals the architecture of the epithelial sodium channel (ENaC).
The Journal of biological chemistry Sep, 2011 | Pubmed ID: 21775436
Four subunits (αβγδ) of the epithelial sodium channel (ENaC) are expressed in the human eye in various locations.
Investigative ophthalmology & visual science Feb, 2012 | Pubmed ID: 22167092
An inhibitory peptide derived from the α-subunit of the epithelial sodium channel (ENaC) shows a helical conformation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology , 2012 | Pubmed ID: 22613977
Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S.
Pflügers Archiv : European journal of physiology Oct, 2012 | Pubmed ID: 22864553
Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ subunit of the human epithelial sodium channel.
The Journal of general physiology Oct, 2012 | Pubmed ID: 22966015
A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect.
American journal of physiology. Lung cellular and molecular physiology Jan, 2013 | Pubmed ID: 23087020
Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC).
Pflügers Archiv : European journal of physiology Feb, 2014 | Pubmed ID: 23842738
Proteolytic Activation of the Human Epithelial Sodium Channel by Trypsin IV and Trypsin I Involves Distinct Cleavage Sites.
The Journal of biological chemistry May, 2014 | Pubmed ID: 24841206
Sensitisation of TRPV4 by PAR2 is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase.
Pflugers Archiv : European journal of physiology Jun, 2014 | Pubmed ID: 24906497
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