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the Affiliated Hospital of Guizhou Medical University

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Medicine

Establishment of A Mouse Model of Aqueous Deficiency Dry Eye
Meng Zhang *1,2, Xiaoyu Tian *1,2, Yiming Wu 3, Liying Zhang 1,2, Lingli Zhang 1,2, Xueer Zheng 1,2, Shangkun Ou 1,2, Hao Gu 1,2
1Department of Ophthalmology, the Affiliated Hospital of Guizhou Medical University, 2School of Clinical Medicine, Guizhou Medical University, 3Department of Biomedical Sciences, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham

Here, we present a method to establish a mouse model of aqueous-deficient dry eye by excising the extraorbital and infraorbital lacrimal glands and evaluate the changes in the ocular surface in aqueous deficiency dry eye.

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