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University of California, Berkeley

4 ARTICLES PUBLISHED IN JoVE

Biology

¹Department of Bioengineering, University of California, Berkeley , ²Department of Bioengineering, University of California, Berkeley; Division of Occupational Medicine, University of California, San Francisco

A new in vitro system for simultaneously loading four tendons in culture is described.

Biology

Chromosomics: Detection of Numerical and Structural Alterations in All 24 Human Chromosomes Simultaneously Using a Novel OctoChrome FISH Assay

Zhiying Ji¹, Luoping Zhang¹

¹Genes and Environment Laboratory, University of California, Berkeley

A novel fluorescence in situ hybridization (FISH) method that simultaneously examines both numerical and structural chromosome alterations, particularly the specific chromosomal translocations associated with leukemia and lymphoma, of all 24 human chromosomes on a single device in one hybridization, is described.

Biology

Fabrication and Use of MicroEnvironment microArrays (MEArrays)

Chun-Han Lin^1,2, Jonathan K. Lee¹, Mark A. LaBarge¹

¹Life Science Division, Lawrence Berkeley National Laboratory, ²Department of Comparative Biochemistry, University of California, Berkeley

A combinatorial functional screening method for gaining insights into the impacts of the molecular composition of microenvironments on cellular functions is described. The method takes advantage of existing microarray-based technologies to generate arrays of defined combinatorial microenvironments that support cell adhesion and functional analysis.

Engineering

Nanomoulding of Functional Materials, a Versatile Complementary Pattern Replication Method to Nanoimprinting

Corsin Battaglia^1,2, Karin Söderström¹, Jordi Escarré¹, Franz-Josef Haug¹, Matthieu Despeisse¹, Christophe Ballif¹

¹Institute of Microengineering (IMT), Photovoltaics and Thin Film Electronics Laboratory, Ecole Polytechnique Fédérale de Lausanne (EPFL), ²Department of Electrical Engineering and Computer Sciences, University of California, Berkeley

We describe a nanomoulding technique which allows low-cost nanoscale patterning of functional materials, materials stacks and full devices. Nanomoulding can be performed on any nanoimprinting setup and can be applied to a wide range of materials and deposition processes.