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University of Central Lancashire

2 ARTICLES PUBLISHED IN JoVE

Chemistry

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Yogita Patil-Sen¹, Amin Sadeghpour², Michael Rappolt², Chandrashekhar V. Kulkarni¹

¹Centre for Materials Science, School of Physical Sciences and Computing, University of Central Lancashire, ²School of Food Science & Nutrition, University of Leeds

We report on a smart application of carbon nanotubes for kinetic stabilization of lipid particles that contain self-assembled nanostructures in their cores. The preparation of lipid particles requires rather low concentrations of carbon nanotubes permitting their use in biomedical applications such as drug delivery.

JoVE Core

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Uffe Bodtger^1,2, José M. Porcel³, Rahul Bhatnagar^4,5, Nick Maskell^4,5, Mohammed Munavvar^6,7, Casper Jensen¹, Paul Frost Clementsen^1,8, Daniel Bech Rasmussen^1,2

¹Respiratory Research Unit PLUZ, Department of Respiratory Medicine, Zealand University Hospital, ²Institute of Regional Health Research, University of Southern Denmark, ³Pleural Medicine Unit, Department of Internal Medicine, Hospital Universitari Arnau de Vilanova, IRBLleida, ⁴Respiratory Department, Southmead Hospital, North Bristol NHS Trust, ⁵Academic Respiratory Unit, University of Bristol, ⁶Lancashire Teaching Hospitals, ⁷University of Central Lancashire, ⁸Centre for HR and Education, Copenhagen Academy for Medical Education and Simulation

Local anesthetic thoracoscopy (LAT) is essential for diagnosing recurrent, undiagnosed pleural effusion when a guideline-based workup fails to provide a specific cause. LAT can be performed as a day-case procedure by chest physicians. Here, we present a step-by-step approach for a successful and safe procedure.