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Walter Reed National Military Medical Center

2 ARTICLES PUBLISHED IN JoVE

Medicine

Inverse Probability of Treatment Weighting (Propensity Score) using the Military Health System Data Repository and National Death Index

Joshua D. Mitchell¹, Brian F. Gage², Nicole Fergestrom³, Eric Novak¹, Todd C. Villines⁴

¹Cardiovascular Division, Washington University School of Medicine, ²General Medical Sciences, Washington University School of Medicine, ³Center for Advancing Population Science, Medical College of Wisconsin, ⁴Cardiology Service, Department of Medicine, Walter Reed National Military Medical Center

When randomized controlled trials are not feasible, a comprehensive health care data source like the Military Health System Data Repository provides an attractive alternative for retrospective analyses. Incorporating mortality data from the national death index and balancing differences between groups using propensity weighting helps reduce biases inherent in retrospective designs.

Neuroscience

Cerebrovascular Reactivity Measurement with Functional Near Infrared Spectroscopy

Franck Amyot¹, Cora Davis¹, Mike Sangobowale⁴, Carol Moore², Erika Silverman⁴, Amir Gandjbakhche³, Ramon Diaz-Arrastia⁴, Kimbra Kenney^1,2

¹National Intrepid Center of Excellence, Walter Reed National Military Medical Center, ²Uniformed Services University of the Health Sciences, ³The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, ⁴University of Pennsylvania Perelman School of Medicine

Presented here is a protocol for imaging and measurement of cerebrovascular reactivity in humans with functional Near Infrared Spectroscopy (fNIRS). fNIRS is a novel imaging modality that captures the concentration changes of hemoglobin species in the brain’s outermost cortex under specific stimuli.