Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed TomographyTodd A. Sasser 1, Sarah E. Chapman 2, Shengting Li 1, Caroline Hudson 2, Sean P. Orton 1, Justin M. Diener 3, Seth T. Gammon 1, Carlos Correcher 4, W. Matthew Leevy 2
1Carestream Molecular Imaging , 2Department of Chemistry and Biochemistry, University of Notre Dame , 3Freimann Life Science Center, University of Notre Dame , 4Research and Development, Oncovision, GEM-Imaging S.A.
Fat content analysis is routinely conducted in studies utilizing murine obesity models. Emerging methods in small animal CT imaging and analysis are providing for longitudinal detail rich fat content analysis. Here we detail step by step procedures for performing small animal CT imaging, analysis, and visualization.
