In Vitro and In Vivo Models to Study Corneal Endothelial-mesenchymal TransitionWei-Ting Ho 1,2, Chien-Chia Su 3, Jung-Shen Chang 3, Shu-Wen Chang 1, Fung-Rong Hu 3, Tzuu-Shuh Jou 2,4, I-Jong Wang 3,4
1Department of Ophthalmology, Far Eastern Memorial Hospital, 2Institute of Clinical Medicine, National Taiwan University, 3Department of Ophthalmology, National Taiwan University Hospital, 4College of Medicine, National Taiwan University
A primary culture of bovine corneal endothelial cells was used to investigate the mechanism of corneal endothelial-mesenchymal transition. Furthermore, a rat corneal endothelium cryoinjury model was used to demonstrate corneal endothelial-mesenchymal transition in vivo.
