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Veterans Affairs New York Harbor

1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

Skin Tattooing As A Novel Approach For DNA Vaccine Delivery
Yung-Nung Chiu 1, Jared M. Sampson 1, Xunqing Jiang 1, Susan B. Zolla-Pazner 2,3, Xiang-Peng Kong 1
1Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, 2Department of Pathology, New York University School of Medicine, 3Healthcare System, Veterans Affairs New York Harbor

Skin tattooing is a potent and safe way to delivery DNA vaccine intradermally. Here, a DNA plasmid encoding EGFP is delivered by tattooing to the skin of a laboratory mouse, and the expression of EGFP in the skin cells is then inspected by confocal microscopy.

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