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Weill Cornell Graduate School of Biomedical Sciences

1 ARTICLES PUBLISHED IN JoVE

Behavior

Stereotaxic Microinjection of Viral Vectors Expressing Cre Recombinase to Study the Role of Target Genes in Cocaine Conditioned Place Preference

Kathryn C. Schierberl^1,2, Anjali M. Rajadhyaksha^1,2

¹Graduate Program in Neuroscience, Weill Cornell Graduate School of Biomedical Sciences, ²Division of Pediatric Neurology, Department of Pediatrics, Weill Cornell Medical College

This article describes how to microinject viral vectors into mouse brain and then test in a conditioned place preference paradigm that includes an acquisition, extinction and reinstatement phase.