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University of Maryland Medical Center

2 ARTICLES PUBLISHED IN JoVE

Medicine

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Adeel Kaiser¹, John G. Eley¹, Nasarachi E. Onyeuku¹, Stephanie R. Rice¹, Carleen C. Wright², Nathan E. McGovern², Megan Sank², Mingyao Zhu¹, Zeljko Vujaskovic¹, Charles B. Simone 2nd¹, Arif Hussain³

¹Department of Radiation Oncology, University of Maryland School of Medicine, ²Department of Radiation Oncology, University of Maryland Medical Center, ³Department of Medicine, University of Maryland School of Medicine, University of Maryland Greenebaum Comprehensive Cancer Center

The fundamentals of radiation planning and delivery for proton therapy using prostate cancer as a model are presented. The application of these principles to other selected disease sites highlights how proton radiotherapy may enhance clinical outcomes for cancer patients.

Medicine

A Simple Cuff Technique for Murine Left Lung Transplantation

Zhongcheng Mei¹, Mojtaba Taheri¹, Elizabeth A. Jacobsen², Wenjun Li^3,4, Andrew E. Gelman^3,4, Daniel Kreisel^3,4, Alexander Sasha Krupnick^1,5

¹Department of Surgery, University of Maryland Medical Center, ²Division of Allergy, Asthma and Clinical Immunology, Mayo Clinic, ³Department of Surgery, Washington University in St. Louis, ⁴Department of Pathology & Immunology, Washington University in St. Louis, ⁵Department of Microbiology and Immunology, University of Maryland Medical Center

The present protocol describes a cuff technique for a mouse left lung transplantation model. This technique has been developed over several years and has performed well, serving effectively in immunological research.