Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector ProteinsBenoît-Joseph Laventie 1, Jutta Nesper 1, Erik Ahrné 2, Timo Glatter 2, Alexander Schmidt 2, Urs Jenal 1
1Focal Area Infection Biology, Biozentrum of the University of Basel, 2Proteomics Core Facility, Biozentrum of the University of Basel
The ubiquitous second messenger c-di-GMP controls growth and behavior of many bacteria. We have developed a novel Capture Compound Mass Spectrometry based technology to biochemically identify and characterize c-di-GMP binding proteins in virtually any bacterial species.
