Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation BioassaysAlvine C. Mehinto 1, B. Sumith Jayasinghe 2, Darcy R. Vandervort 1, Nancy D. Denslow 2, Keith A. Maruya 1
1Southern California Coastal Water Research Project Authority, 2Department of Physiological Sciences, University of Florida
A protocol to screen for endocrine activity in organic extracts of water samples, including treated wastewater effluent and surface (receiving) water, was adapted using commercially available division-arrested ("freeze and thaw") in vitro transactivation bioassays.
