Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug DeliveryLei Nie 1,2, Shaolan Sun 1, Meng Sun 1, Qiuju Zhou 3, Zongwen Zhang 3, Lingyun Zheng 3, Lingling Wang 3
1College of Life Sciences, Xinyang Normal University, 2Department of Imaging & Pathology, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven, 3Analysis & Testing Center, Xinyang Normal University
In this protocol, doxorubicin-loaded AS1411-g-PEI-g-PEG modified gold nanoparticles are synthesized via three-step amide reactions. Then, doxorubicin is loaded and delivered to target cancer cells for cancer therapy.
