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Korea Institute of Radiological and Medical Sciences

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Preparing a 68Ga-labeled Arginine Glycine Aspartate (RGD)-peptide for Angiogenesis
Ki-Hye Jung 1, Yong Jin Lee 1, Jung Young Kim 1, Kyo Chul Lee 1, Ji-Ae Park 1, Jae Yong Choi 1
1Division of Applied RI, Korea Institute of Radiological and Medical Sciences

The αvβ3 integrin is a type of adhesion protein that is highly expressed on activated endothelial cells undergoing angiogenesis. Thus, evaluating the integrity of the integrin is of great interest in oncology. Here, we introduce a method to prepare 68Ga-labeled radiopeptides and a method to assess its biological effectiveness.

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