Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain InjuryMatthew J. McGuire 1, Steven M. Gertz 1, Jolie D. McCutcheon 2, Chelsea R. Richardson 3, David J. Poulsen 1
1Department of Neurosurgery, Jacobs School of Medicine and Biomedical Science, 2Comparative Medicine Laboratory Animal Facilities, University at Buffalo, 3emka Technologies
Here we present a protocol to induce severe TBI with the lateral fluid percussion injury (FPI) model in adult, male Wistar rats. We also demonstrate the use of a wireless telemetry system to collect continuous video-EEG recordings and monitor for epileptiform discharges consistent with post-traumatic epileptogenesis.
