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Hospital Sirio-Libanes

1 ARTICLES PUBLISHED IN JoVE

Neuroscience

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Daniele de Paula Faria¹, Caroline Cristiano Real¹, Larissa Estessi de Souza¹, Alexandre Teles Garcez², Fabio Luis Navarro Marques¹, Carlos Alberto Buchpiguel¹

¹Laboratory of Nuclear Medicine (LIM-43), Departamento de Radiologia e Oncologia, Faculdade de Medicina, Universidade de Sao Paulo, ²Nuclear Medicine Division, Hospital Sirio-Libanes

This protocol has the aim of monitoring in vivo myelin changes (demyelination and remyelination) by positron emission tomography (PET) imaging in an animal model of multiple sclerosis.