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Telethon Kids Institute

2 ARTICLES PUBLISHED IN JoVE

Medicine

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Mar Janna Dahl¹, Stefano Robbiani², Chiara Veneroni², Anna Lavizzari³, Sebastian Amos¹, Gabrielle C. Musk^1,4, Helen Kershaw⁴, Jonathan W. Davis^5,6, Fabio Mosca³, Peter B. Noble¹, Raffaele Dellacà^*2, J. Jane Pillow^*1,6

¹School of Human Sciences, The University of Western Australia, ²Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano University, ³NICU, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, ⁴Animal Care Services, The University of Western Australia, ⁵Medical School, University of Western Australia, ⁶Telethon Kids Institute

Optimization of occlusion pressure and duration required to improve lung hypoplasia with tracheal occlusion is essential to improve in utero corrective treatments for congenital diaphragmatic hernia (CDH). This study reports a new method for continuous measurement of the tracheal pressure in an occluded and unoccluded fetal lamb surgical model of CDH.

Medicine

Amplitude-Integrated EEG in Infants at Risk of Hypoxic-Ischemic Encephalopathy: A Feasibility Study in Road and Air Transport in Western Australia

Alexander Wilson^1,2,3, Varuna Chaudhary^1,2,3, Ela Chakkrapani^4,5, Mary O'Dea^6,7, Jonathan Davis^1,2,3,8,9,10

¹Government of Western Australia, Child and Adolescent Health Service, ²Newborn Emergency Transport Service Western Australia (NETS WA), ³Perth Children's Hospital, ⁴University of Bristol, ⁵St Michael's Hospital, ⁶Coombe Hospital, ⁷Children's Health Ireland, ⁸Telethon Kids Institute, ⁹King Edward Memorial Hospital, ¹⁰University of Western Australia

Here, we present a feasibility study to assess a portable amplitude-integrated electroencephalogram (aEEG) recording system during the transport of infants with suspected hypoxic ischemic encephalopathy (HIE).