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Drexel University

2 ARTICLES PUBLISHED IN JoVE

Bioengineering

Three-dimensional Cell Culture Model for Measuring the Effects of Interstitial Fluid Flow on Tumor Cell Invasion

Alimatou M. Tchafa¹, Arpit D. Shah¹, Shafei Wang¹, Melissa T. Duong¹, Adrian C. Shieh¹

¹School of Biomedical Engineering, Science and Health Systems, Drexel University

Interstitial fluid flow is elevated in solid tumors and can modulate tumor cell invasion. Here we describe a technique to apply interstitial fluid flow to cells embedded in a matrix and then measure its effects on cell invasion. This technique can be easily adapted to study other systems.

Medicine

Minimal Erythema Dose (MED) Testing

Carolyn J. Heckman¹, Rachel Chandler², Jacqueline D. Kloss³, Amy Benson², Deborah Rooney², Teja Munshi¹, Susan D. Darlow¹, Clifford Perlis⁴, Sharon L. Manne⁵, David W. Oslin²

¹Cancer Prevention and Control Program, Fox Chase Cancer Center , ²Department of Psychiatry, University of Pennsylvania , ³Department of Psychology, Drexel University , ⁴Department of Medicine, Fox Chase Cancer Center , ⁵Cancer Prevention and Control Program, The Cancer Institute of New Jersey

This article describes how to conduct minimal erythema dose (MED) testing in order to determine the lowest dose of ultraviolet radiation that will cause erythema (burning) when administered to an individual.