Mouse Hindbrain Ex Vivo Culture to Study Facial Branchiomotor Neuron MigrationMiguel Tillo 1, Quenten Schwarz 1,2, Christiana Ruhrberg 1
1UCL Institute of Ophthalmology, University College London, 2Department of Human Immunology, Centre for Cancer Biology, South Australia
Embryonic neurons are born in the ventricular zone of the neural tube, but migrate to reach appropriate targets. Facial branchiomotor (FBM) neurons are a useful model to study neuronal migration. This protocol describes the wholemount ex vivo culture of mouse embryo hindbrains to investigate mechanisms that regulate FBM migration.
