Orthotopic Hind Limb Transplantation in the MouseGeorg J. Furtmüller *1, Byoungchol Oh *1, Johanna Grahammer *2, Cheng-Hung Lin 3, Robert Sucher 4, Madeline L. Fryer 1, Giorgio Raimondi 1, W.P. Andrew Lee 1, Gerald Brandacher 1
1Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA) Laboratory, Johns Hopkins University School of Medicine, 2Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, 3Center for Vascularized Composite Allotransplantation, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital and School of Medicine, 4Department of General, Visceral and Transplant Surgery, Charite Berlin
This novel model for orthotopic hind limb transplantation in the mouse, applying a non-suture cuff technique for super-microvascular anastomosis, provides a powerful tool for in vivo mechanistic immunological research related to vascularized composite allotransplantation (VCA).
