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U.S. Army Center for Environmental Health Research

1 ARTICLES PUBLISHED IN JoVE

Environment

Preparation and Testing of Impedance-based Fluidic Biochips with RTgill-W1 Cells for Rapid Evaluation of Drinking Water Samples for Toxicity

Linda M. Brennan¹, Mark W. Widder¹, Michael K. McAleer², Michael W. Mayo², Alex P. Greis², William H. van der Schalie¹

¹U.S. Army Center for Environmental Health Research, ²Nanohmics, Inc.

This manuscript describes how to prepare fluidic biochips with Rainbow trout gill epithelial cells for use in a field portable electric cell-substrate impedance sensor. The protocol for running a rapid drinking water toxicity test with the sensor is also described.