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Izon Science Limited

1 ARTICLES PUBLISHED IN JoVE

Bioengineering

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Emma L. C. J. Blundell¹, Robert Vogel^2,3, Mark Platt¹

¹Department of Chemistry, School of Science, Loughborough University, ²Izon Science Limited, ³School of Mathematics and Physics, The University of Queensland

Here we use a polyurethane tunable nanopore integrated into a resistive pulse sensing technique to characterize nanoparticles surface chemistry via the measurement of particle translocation velocities, which can be used to determine the zeta potential of individual nanoparticles.