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Huacells Corp

2 ARTICLES PUBLISHED IN JoVE

Bioengineering

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

Fenfang Li¹, Fang Yuan², Georgy Sankin¹, Chen Yang¹, Pei Zhong¹

¹Mechanical Engineering and Materials Science, Duke University, ²Huacells Corp

A microfluidic chip was fabricated to produce pairs of gold dots for tandem bubble generation and fibronectin-coated islands for single-cell patterning nearby. The resultant flow field was characterized by particle image velocimetry and was employed to study various bioeffects, including cell membrane poration, membrane deformation, and intracellular calcium response.

Engineering

New Application of an Atmospheric Pressure Plasma Jet as a Neuro-protective Agent Against Glucose Deprivation-induced Injury of SH-SY5Y Cells

Xu Yan^*1,3,4,5, Zhaozhong Meng^*2, Jiting Ouyang², Yajun Qiao², Fang Yuan^1,3,4,5

¹Department of Pathophysiology, Beijing Neurosurgical Institute/Beijing Tiantan Hospital, Capital Medical University, ²School of Physics, Beijing Institute of Technology, ³Beijing Key Laboratory of Central Nervous System Injury, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, ⁴Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing Tiantan Hospital, Capital Medical University, ⁵China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University

A protocol for the neuroprotective application of low-dose atmospheric pressure plasma treatment on glucose deprivation-induced SH-SY5Y injuries.