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Zurich University of Applied Sciences, School of Life Sciences and Facility Management

2 ARTICLES PUBLISHED IN JoVE

JoVE Core

A Cost-effective and Reliable Method to Predict Mechanical Stress in Single-use and Standard Pumps

Ina Dittler¹, Wolfgang Dornfeld², Reto Schöb², Jared Cocke³, Jürgen Rojahn³, Matthias Kraume⁴, Dieter Eibl¹

¹Institute of Biotechnology, School of Life Sciences and Facility Management, Zurich University of Applied Sciences, ²Levitronix Ltd., ³SOPAT Ltd., ⁴Institute of Chemical and Process Engineering, Technische Universität Berlin

Shear stress investigations on an oil-water emulsion system result in drop breakup over the experimental time. To count drop sizes in pumping processes, the suitability of inline endoscopy was successfully demonstrated in this protocol.

JoVE Core

Power Input Measurements in Stirred Bioreactors at Laboratory Scale

Stephan C. Kaiser¹, Sören Werner², Valentin Jossen², Katharina Blaschczok², Dieter Eibl²

¹Finesse, Thermo Fisher Scientific, ²Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, School of Life Sciences and Facility Management

The power input in stirred bioreactors can be measured through the torque that acts on the impeller shaft during rotation. This manuscript describes how an air bearing can be used to effectively reduce friction losses observed in mechanical seals and improve the accuracy of power input measurements in small-scale vessels.