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Monash University, Melbourne VIC 3800, Australia.

1 ARTICLES PUBLISHED IN JoVE

JoVE Journal

Quantitative Approaches for Studying Cellular Structures and Organelle Morphology in Caenorhabditis elegans

Jean-Sébastien Teoh^*1, Ming S. Soh^*1, Joseph J. Byrne^*1, Brent Neumann¹

¹Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne VIC 3800, Australia.

This study outlines quantitative measurements of synaptic size and localization, muscle morphology, and mitochondrial shape in C. elegans using freely available image processing tools. This approach allows future studies in C. elegans to quantitatively compare the extent of tissue and organelle structural changes as a result of genetic mutations.