Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid InterfaceAmelie Tsoutsoulopoulos 1, Katrin Gohlsch 2, Niklas Möhle 3, Andreas Breit 2, Sebastian Hoffmann 5, Olaf Krischenowski 3,4, Harald Mückter 2, Thomas Gudermann 2, Horst Thiermann 1, Michaela Aufderheide 3,4, Dirk Steinritz 1,2
1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, University of Munich, 3Cultex Laboratories GmbH, 4Cultex Technologies GmbH (formerly Cultex Laboratories GmbH), 5seh consulting + services
We present a robust, transferable and predictive in vitro exposure system for the screening and monitoring of airborne particles concerning their acute pulmonary cytotoxicity by exposing cultivated human lung cells at the air-liquid interface (ALI).
