Development of a Larval Zebrafish Infection Model for Clostridioides difficileJunkai Li 1, Can M. Ünal 2, Kazuhiko Namikawa 1, Michael Steinert 3,4,5, Reinhard W. Köster 1
1Division of Cellular and Molecular Neurobiology, Zoological Institute, Technische Universität Braunschweig, 2Department of Molecular Biotechnology, Turkish-German University, 3Institut für Mikrobiologie, Technische Universität Braunschweig, 4Braunschweig Integrated Centre of Systems Biology, 5Helmholtz Centre for Infection Research
Presented here is a safe and effective method to infect zebrafish larvae with fluorescently labeled anaerobic C. difficile by microinjection and noninvasive microgavage.
