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Radboud University Medical Center, Radboud Institute for Health Sciences, Department of Plastic Surgery, Nijmegen, The Netherlands

1 ARTICLES PUBLISHED IN JoVE

Neuroscience

Maximum Isometric Tetanic Force Measurement of the Tibialis Anterior Muscle in the Rat

Meiwand Bedar^1,2, Tiam M. Saffari^1,2, Patricia F. Friedrich¹, Guilherme Giusti¹, Allen T. Bishop¹, Alexander Y. Shin¹

¹Department of Orthopedic Surgery, Mayo Clinic, ²Radboud University Medical Center, Radboud Institute for Health Sciences, Department of Plastic Surgery, Nijmegen, The Netherlands

Evaluation of motor recovery remains the benchmark outcome measure in experimental peripheral nerve studies. The isometric tetanic force measurement of the tibialis anterior muscle in the rat is an invaluable tool to assess functional outcomes after reconstruction of sciatic nerve defects. The methods and nuances are detailed in this article.