Ex Vivo Release of Calcitonin Gene-Related Peptide from the Trigeminovascular System in RodentsRikke H. Rasmussen 1, Inger Jansen-Olesen 1, David M. Kristensen 1,2,3, Sarah L. Christensen 1
1Danish Headache Center, Department of Neurology, Rigshospitalet, University of Copenhagen, 2EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail), Univ Rennes, Inserm, 3Department of Biology, Section of Cell Biology and Physiology, University of Copenhagen
The present protocol describes the ex vivo calcitonin gene-related peptide (CGRP) release model and the strategy to quantify the effect of pharmacological agents on the amount of CGRP released from the trigeminovascular system in rodents.
