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Institute of Basic Science (IBS)

2 ARTICLES PUBLISHED IN JoVE

Chemistry

Liquid-cell Transmission Electron Microscopy for Tracking Self-assembly of Nanoparticles

Byung Hyo Kim^1,2, Junyoung Heo^1,2, Won Chul Lee³, Jungwon Park^1,2

¹Center for Nanoparticle Research, Institute for Basic Science (IBS), ²School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, ³Department of Mechanical Engineering, Hanyang University

Here we introduce experimental protocols for the real-time observation of a self-assembly process using liquid-cell transmission electron microscopy.

Engineering

Fabrication of Micro-Patterned Chip with Controlled Thickness for High-Throughput Cryogenic Electron Microscopy

Min-Ho Kang^1,2, Minyoung Lee^3,4, Sungsu Kang^3,4, Jungwon Park^3,4,5,6

¹Department of Biomedical-Chemical Engineering, The Catholic University of Korea, ²Department of Biotechnology, The Catholic University of Korea, ³School of Chemical and Biological Engineering, and Institute of Chemical Processes, Seoul National University, ⁴Center for Nanoparticle Research, Institute of Basic Science (IBS), ⁵Institute of Engineering Research, College of Engineering, Seoul National University, ⁶Advanced Institutes of Convergence Technology, Seoul National University

A newly developed micro-patterned chip with graphene oxide windows is fabricated by applying microelectromechanical system techniques, enabling efficient and high-throughput cryogenic electron microscopy imaging of various biomolecules and nanomaterials.