Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion

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433 Views

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09:47 min

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June 14th, 2024

DOI :

10.3791/66702-v

June 14th, 2024

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Doug A. Gouchoe*¹^,², Yong Gyu Lee*¹^,², Alisyn Greenfield³, Clayton Cuddington³, Jung-Lye Kim¹^,², Sylvester M. Black¹, Andre F. Palmer³, Bryan A. Whitson¹^,²

¹COPPER Laboratory, Department of Surgery, The Ohio State University Wexner Medical Center, ²Division of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, ³William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering, The Ohio State University

Podsumowanie

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Ex Vivo Lung Perfusion

EVLP

Polymerized Hemoglobin

Donor Organ Evaluation

Fluid Homeostasis

Metabolic Support

Pulmonary Edema

Hemoglobin based Oxygen Carrier HBOC

Perfusate Candidates

Donor Pool Expansion

Perfusion Techniques

Rozdziały w tym wideo

0:00

Introduction

1:25

Setup of an Ex Vivo Lung Perfusion (EVLP) Circuit with PolyhHb for Lung Perfusion in Rats

2:56

Procurement and Cannulation of Donor Rat Lung Block for Ex Vivo Lung Perfusion

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