Department NeuroFarBa,
Division of Pharmacology,
Department of Neurosciences,
Psychology,
Drugs and Child Health,
Department NeuroFarBa, Division of Pharmacology,
Department of Neurosciences, Psychology, Drugs and Child Health
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Does recombinant human interleukin-11 exert direct electrophysiologic effects on single human atrial myocytes?
Journal of cardiovascular pharmacology Mar, 2002 | Pubmed ID: 11862122
Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes.
The Journal of physiology Nov, 2002 | Pubmed ID: 12433951
Selectivity of different calcium antagonists on T- and L-type calcium currents in guinea-pig ventricular myocytes.
Pharmacological research : the official journal of the Italian Pharmacological Society Dec, 2002 | Pubmed ID: 12457621
Treatment with irbesartan counteracts the functional remodeling of ventricular myocytes from hypertensive rats.
Journal of cardiovascular pharmacology May, 2003 | Pubmed ID: 12717113
Prenatal exposure to carbon monoxide affects postnatal cellular electrophysiological maturation of the rat heart: a potential substrate for arrhythmogenesis in infancy.
Circulation Jan, 2004 | Pubmed ID: 14718404
Angiotensin AT2 receptor: the younger sibling attracts attention.
Cardiovascular research Apr, 2004 | Pubmed ID: 15023548
Restoration of cardiomyocyte functional properties by angiotensin II receptor blockade in diabetic rats.
Diabetes Jul, 2004 | Pubmed ID: 15220222
Atrial natriuretic peptide modulates the hyperpolarization-activated current (If) in human atrial myocytes.
Cardiovascular research Aug, 2004 | Pubmed ID: 15276478
n-3 polyunsaturated fatty acids supplementation decreases asymmetric dimethyl arginine and arachidonate accumulation in aging spontaneously hypertensive rats.
European journal of nutrition Sep, 2005 | Pubmed ID: 15368071
Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current.
Bioorganic & medicinal chemistry Feb, 2005 | Pubmed ID: 15670930
Pharmacological modulation of the hyperpolarization-activated current (I f) in human atrial myocytes: focus on G protein-coupled receptors.
Journal of molecular and cellular cardiology Mar, 2005 | Pubmed ID: 15733905
[The pacemaker current If: a novel pharmacological target for cardiologists].
Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology Jul, 2005 | Pubmed ID: 16082824
Functional remodeling in post-myocardial infarcted rats: focus on beta-adrenoceptor subtypes.
Journal of molecular and cellular cardiology Feb, 2006 | Pubmed ID: 16427077
I(f) in non-pacemaker cells: role and pharmacological implications.
Pharmacological research : the official journal of the Italian Pharmacological Society May, 2006 | Pubmed ID: 16713285
Tension generation and relaxation in single myofibrils from human atrial and ventricular myocardium.
Pflügers Archiv : European journal of physiology Apr, 2007 | Pubmed ID: 17123098
Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach.
Stem cells (Dayton, Ohio) May, 2007 | Pubmed ID: 17255522
Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2007 | Pubmed ID: 17284482
NADPH oxidase-dependent redox signaling in human heart failure: relationship between the left and right ventricle.
Journal of molecular and cellular cardiology Apr, 2007 | Pubmed ID: 17346742
ATP modulates cell proliferation and elicits two different electrophysiological responses in human mesenchymal stem cells.
Stem cells (Dayton, Ohio) Jul, 2007 | Pubmed ID: 17446563
Dopamine agonists and valvular heart disease.
The New England journal of medicine Apr, 2007 | Pubmed ID: 17447276
Fetal bovine serum enables cardiac differentiation of human embryonic stem cells.
Differentiation; research in biological diversity Oct, 2007 | Pubmed ID: 17459089
Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation.
Cardiovascular research Dec, 2007 | Pubmed ID: 17854786
Expression of the hyperpolarization-activated current, I(f), in cultured adult rat ventricular cardiomyocytes and its modulation by hypertrophic factors.
Pharmacological research : the official journal of the Italian Pharmacological Society Feb, 2008 | Pubmed ID: 18255311
Do amniotic fluid-derived stem cells differentiate into neurons in vitro?
Nature biotechnology Mar, 2008 | Pubmed ID: 18327228
Holt-oram syndrome and atrial fibrillation: opening the (T)-box.
Circulation research Jun, 2008 | Pubmed ID: 18535267
Molecular basis of funny current (If) in normal and failing human heart.
Journal of molecular and cellular cardiology Aug, 2008 | Pubmed ID: 18556018
Role of potassium currents in cardiac arrhythmias.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Oct, 2008 | Pubmed ID: 18653669
Beating to time: calcium clocks, voltage clocks, and cardiac pacemaker activity.
American journal of physiology. Heart and circulatory physiology Mar, 2009 | Pubmed ID: 19151259
Electrophysiologic changes in heart failure: focus on pacemaker channels.
Canadian journal of physiology and pharmacology Feb, 2009 | Pubmed ID: 19234571
Modulation of cardiac ionic homeostasis by 3-iodothyronamine.
Journal of cellular and molecular medicine Sep, 2009 | Pubmed ID: 19298522
From in vivo plasma composition to in vitro cardiac electrophysiology and in silico virtual heart: the extracellular calcium enigma.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences Jun, 2009 | Pubmed ID: 19414453
Identifying needs and opportunities for advancing translational research in cardiovascular disease.
Cardiovascular research Aug, 2009 | Pubmed ID: 19502281
Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.
Cardiovascular diabetology , 2009 | Pubmed ID: 19545435
Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin.
The Journal of nutritional biochemistry Aug, 2010 | Pubmed ID: 19616928
Prenatal exposure to carbon monoxide temporarily impairs maturation of rat cardiomyocytes: Electrophysiological evidence.
Experimental and clinical cardiology , 2005 | Pubmed ID: 19641682
I(f) channels as a therapeutic target in heart disease.
Future cardiology Nov, 2007 | Pubmed ID: 19804286
Enhanced ROS production by NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure.
Biochimica et biophysica acta Mar, 2010 | Pubmed ID: 19892017
Cardiac and electrophysiological effects of primary and refined extracts from Leonurus cardiaca L. (Ph.Eur.).
Planta medica Apr, 2010 | Pubmed ID: 19918711
Electrophysiological characterization of isolated human atrial myocytes exposed to tegaserod.
Basic & clinical pharmacology & toxicology May, 2010 | Pubmed ID: 20050846
Italy's stem-cell challenge gaining momentum.
Nature Feb, 2010 | Pubmed ID: 20148012
Effects of chronic atrial fibrillation on active and passive force generation in human atrial myofibrils.
Circulation research Jul, 2010 | Pubmed ID: 20466979
Nitric oxide/reactive oxygen species generation and nitroso/redox imbalance in heart failure: from molecular mechanisms to therapeutic implications.
Antioxidants & redox signaling Jan, 2011 | Pubmed ID: 20624031
Prenatal exposure to carbon monoxide delays postnatal cardiac maturation.
Laboratory investigation; a journal of technical methods and pathology Nov, 2010 | Pubmed ID: 20644522
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2010 | Pubmed ID: 20720158
Design, synthesis, and preliminary biological evaluation of new isoform-selective f-current blockers.
Journal of medicinal chemistry Sep, 2010 | Pubmed ID: 20795648
Heart rate reduction with ivabradine prevents the global phenotype of left ventricular remodeling.
American journal of physiology. Heart and circulatory physiology Jan, 2011 | Pubmed ID: 20952661
The effect of losartan treatment on the response of diabetic cardiomyocytes to ATP depletion.
Pharmacological research : the official journal of the Italian Pharmacological Society Mar, 2011 | Pubmed ID: 21078391
Growth factor-induced mobilization of cardiac progenitor cells reduces the risk of arrhythmias, in a rat model of chronic myocardial infarction.
PloS one , 2011 | Pubmed ID: 21445273
Electrophysiological effects of ivabradine in dog and human cardiac preparations: potential antiarrhythmic actions.
European journal of pharmacology Oct, 2011 | Pubmed ID: 21821019
Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue.
British journal of pharmacology May, 2012 | Pubmed ID: 22091830
Action potential propagation in transverse-axial tubular system is impaired in heart failure.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2012 | Pubmed ID: 22451916
Mathematical modelling of the action potential of human embryonic stem cell derived cardiomyocytes.
Biomedical engineering online , 2012 | Pubmed ID: 22929020
Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy.
Circulation Feb, 2013 | Pubmed ID: 23271797
Molecular and functional evidence of HCN4 and caveolin-3 interaction during cardiomyocyte differentiation from human embryonic stem cells.
Stem cells and development Jun, 2013 | Pubmed ID: 23311301
Chronic atrial fibrillation alters the functional properties of If in the human atrium.
Journal of cardiovascular electrophysiology Dec, 2013 | Pubmed ID: 23869794
Human amniotic fluid stem cell differentiation along smooth muscle lineage.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2013 | Pubmed ID: 23995291
Response to letter regarding article, "Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy".
Circulation Sep, 2013 | Pubmed ID: 24002721
Altered calcium regulation in isolated cardiomyocytes from Egr-1 knock-out mice.
Canadian journal of physiology and pharmacology Dec, 2013 | Pubmed ID: 24289086
Regulation of intracellular Na(+) in health and disease: pathophysiological mechanisms and implications for treatment.
Global cardiology science & practice , 2013 | Pubmed ID: 24689024
Impact of detubulation on force and kinetics of cardiac muscle contraction.
The Journal of general physiology Jun, 2014 | Pubmed ID: 24863933
Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2014 | Pubmed ID: 25288764
T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.
International journal of molecular sciences Sep, 2016 | Pubmed ID: 27598150
Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation.
Scientific reports 10, 2016 | Pubmed ID: 27748433
Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair.
Small (Weinheim an der Bergstrasse, Germany) 12, 2017 | Pubmed ID: 29045016
Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction.
Circulation research 04, 2019 | Pubmed ID: 30732554
Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrates.
International journal of molecular sciences Aug, 2019 | Pubmed ID: 31382622
Optical clearing in cardiac imaging: A comparative study.
Progress in biophysics and molecular biology Aug, 2021 | Pubmed ID: 34358555
Fast Optical Investigation of Cardiac Electrophysiology by Parallel Detection in Multiwell Plates.
Frontiers in physiology , 2021 | Pubmed ID: 34539428
Francesco Giardini*,1,
Erica Lazzeri*,1,
Camilla Olianti*,1,
Giada Beconi1,
Irene Costantini1,2,
Ludovico Silvestri1,3,4,
Elisabetta Cerbai1,5,
Francesco S. Pavone1,3,4,
Leonardo Sacconi1,3,6
1, European Laboratory for Non-Linear Spectroscopy,
2Department of Biology, University of Florence,
3, National Institute of Optics, National Research Council,
4Department of Physics and Astronomy, University of Florence,
5Department of Neurosciences, Psychology, Drugs and Child Health, University of Florence,
6Institute for Experimental Cardiovascular Medicine, Faculty of Medicine, University of Freiburg
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