Joan W. Conaway

Roles of SCF and VHL ubiquitin ligases in regulation of cell growth.

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.

A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor.

The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription.

Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex.

von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination.

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.

Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A.

The mammalian Mediator complex and its role in transcriptional regulation.

Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes.

RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors.

Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL.

RNA polymerase II: a "nobel" enzyme demystified.

YY1 functions with INO80 to activate transcription.

Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.

Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.

Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics.

Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.

Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.

MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression.

Direct inhibition of RNA polymerase II transcription by RECQL5.

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler.

Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID.

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation.

Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.

When transcription meets recombination: a lesson from the human RECQ protein complexes.

O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1.

Thematic minireview series on computational systems biology.

Human mediator subunit MED26 functions as a docking site for transcription elongation factors.

The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters.

Introduction to theme "Chromatin, epigenetics, and transcription".

The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME.

Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation.

Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate.

Immunoaffinity purification of protein complexes from Mammalian cells.

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.

Transcriptional properties of mammalian elongin A and its role in stress response.

Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes.

Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex.

Subunit architecture and functional modular rearrangements of the transcriptional mediator complex.