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Roles of SCF and VHL ubiquitin ligases in regulation of cell growth.
Progress in molecular and subcellular biology , 2002 | Pubmed ID: 11908068
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature Apr, 2002 | Pubmed ID: 11961546
A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12048197
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2002 | Pubmed ID: 12351678
The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription.
Advances in cancer research , 2002 | Pubmed ID: 12374282
Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12538644
von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2003 | Pubmed ID: 12604794
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Molecular cell Jun, 2004 | Pubmed ID: 15175151
ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15590664
Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15611125
The mammalian Mediator complex and its role in transcriptional regulation.
Trends in biochemical sciences May, 2005 | Pubmed ID: 15896743
Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes.
Methods (San Diego, Calif.) Dec, 2006 | Pubmed ID: 17101442
RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors.
The EMBO journal Nov, 2006 | Pubmed ID: 17110932
Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL.
The Journal of biological chemistry Feb, 2007 | Pubmed ID: 17150956
RNA polymerase II: a "nobel" enzyme demystified.
Molecular cell Dec, 2006 | Pubmed ID: 17157247
YY1 functions with INO80 to activate transcription.
Nature structural & molecular biology Sep, 2007 | Pubmed ID: 17721549
Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.
The Journal of biological chemistry Feb, 2008 | Pubmed ID: 18077452
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.
The Journal of biological chemistry Mar, 2008 | Pubmed ID: 18187417
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18218781
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.
Molecular cell Sep, 2008 | Pubmed ID: 18922472
Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.
The EMBO journal Dec, 2008 | Pubmed ID: 19037258
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression.
The Journal of biological chemistry Jan, 2009 | Pubmed ID: 19049968
Direct inhibition of RNA polymerase II transcription by RECQL5.
The Journal of biological chemistry Aug, 2009 | Pubmed ID: 19570979
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2009 | Pubmed ID: 19666485
Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID.
The Journal of biological chemistry Nov, 2009 | Pubmed ID: 19805548
Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2009 | Pubmed ID: 19920177
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.
The Journal of biological chemistry Feb, 2010 | Pubmed ID: 20018852
AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Molecular cell Feb, 2010 | Pubmed ID: 20159561
When transcription meets recombination: a lesson from the human RECQ protein complexes.
F1000 biology reports , 2009 | Pubmed ID: 20948612
O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1.
Cell Feb, 2011 | Pubmed ID: 21295698
Thematic minireview series on computational systems biology.
The Journal of biological chemistry Jul, 2011 | Pubmed ID: 21566145
Human mediator subunit MED26 functions as a docking site for transcription elongation factors.
Cell Jul, 2011 | Pubmed ID: 21729782
The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters.
The EMBO journal Sep, 2011 | Pubmed ID: 21822215
Introduction to theme "Chromatin, epigenetics, and transcription".
Annual review of biochemistry , 2012 | Pubmed ID: 22404631
The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME.
PloS one , 2012 | Pubmed ID: 22912744
Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation.
Cell reports Nov, 2012 | Pubmed ID: 23122963
Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate.
The Journal of biological chemistry Dec, 2012 | Pubmed ID: 23132853
Immunoaffinity purification of protein complexes from Mammalian cells.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23436370
A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.
Nature structural & molecular biology May, 2013 | Pubmed ID: 23563140
Transcriptional properties of mammalian elongin A and its role in stress response.
The Journal of biological chemistry Aug, 2013 | Pubmed ID: 23828199
Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes.
PLoS genetics Nov, 2013 | Pubmed ID: 24244196
Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2013 | Pubmed ID: 24297934
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex.
Cell Jun, 2014 | Pubmed ID: 24882805