Paul R. Selvin

Single molecule FRET reveals pore size and opening mechanism of a mechano-sensitive ion channel.

Motor domain phosphorylation modulates kinesin-1 transport.

Holding two heads together: stability of the myosin II rod measured by resonance energy transfer between the heads.

Principles and biophysical applications of lanthanide-based probes.

Thiol-reactive lanthanide chelates for phasing protein X-ray diffraction data.

Lighting up single ion channels.

An actin-dependent conformational change in myosin.

Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization.

Thiol-reactive luminescent lanthanide chelates: part 2.

Does the S2 rod of myosin II uncoil upon two-headed binding to actin? A leucine-zippered HMM study.

Kinesin walks hand-over-hand.

3D Super-Resolution Imaging with Blinking Quantum Dots.

Single-molecule high-resolution imaging with photobleaching.

Myosin VI steps via a hand-over-hand mechanism with its lever arm undergoing fluctuations when attached to actin.

Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration.

Carbostyril derivatives as antenna molecules for luminescent lanthanide chelates.

Kinesin: walking, crawling or sliding along?

Kinesin and dynein move a peroxisome in vivo: a tug-of-war or coordinated movement?

Interhead distance measurements in myosin VI via SHRImP support a simplified hand-over-hand model.

Fluorescence imaging with one nanometer accuracy: application to molecular motors.

Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer.

Step-size is determined by neck length in myosin V.

Full-length myosin VI dimerizes and moves processively along actin filaments upon monomer clustering.

Adaptability of myosin V studied by simultaneous detection of position and orientation.

Defocused orientation and position imaging (DOPI) of myosin V.

Maximum likelihood estimation of molecular motor kinetics from staircase dwell-time sequences.

Extracting dwell time sequences from processive molecular motor data.

Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer.

Rapid DNA mapping by fluorescent single molecule detection.

The unique insert at the end of the myosin VI motor is the sole determinant of directionality.

New fluorescent tools for watching nanometer-scale conformational changes of single molecules.

Microtubule binding by dynactin is required for microtubule organization but not cargo transport.

Tracking melanosomes inside a cell to study molecular motors and their interaction.

Determination of haplotypes from single DNA molecules: a method for single-molecule barcoding.

How myosin VI coordinates its heads during processive movement.

Three-dimensional particle tracking via bifocal imaging.

Single-molecule fluorescence to study molecular motors.

The mitotic kinesin CENP-E is a processive transport motor.

New 9- or 10-dentate luminescent lanthanide chelates.

Extent of voltage sensor movement during gating of shaker K+ channels.

The role of microtubule movement in bidirectional organelle transport.

FIONA on Caenorhabditis elegans.

Polarization effect on position accuracy of fluorophore localization.

Why kinesin is so processive.

Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach.

Myosin VI undergoes a 180 degrees power stroke implying an uncoupling of the front lever arm.

Super-accuracy and super-resolution getting around the diffraction limit.

Formation of salt bridges mediates internal dimerization of myosin VI medial tail domain.

Counting bungarotoxin binding sites of nicotinic acetylcholine receptors in mammalian cells with high signal/noise ratios.

Improved hidden Markov models for molecular motors, part 1: basic theory.

Improved hidden Markov models for molecular motors, part 2: extensions and application to experimental data.

Equipment Setup for Fluorescence Imaging with One-Nanometer Accuracy (FIONA).

Data Analysis Methods for Fluorescence Imaging with One-Nanometer Accuracy (FIONA).

Constructing Sample Chambers for Fluorescence Imaging with One-Nanometer Accuracy (FIONA).

Fluorescence Imaging with One-Nanometer Accuracy (FIONA) of Cy3-DNA under Deoxygenation Conditions.

Fluorescence Imaging with One-Nanometer Accuracy (FIONA).

Single-virus tracking reveals a spatial receptor-dependent search mechanism.

Extension of a three-helix bundle domain of myosin VI and key role of calmodulins.

Molecular motors one at a time: FIONA to the rescue.

Fluorescence imaging with one nanometer accuracy: in vitro and in vivo studies of molecular motors.

Two-photon 3D FIONA of individual quantum dots in an aqueous environment.

Single-molecule-based super-resolution images in the presence of multiple fluorophores.

Biomimetic surface engineering of lanthanide-doped upconversion nanoparticles as versatile bioprobes.

Multicolor super-resolution DNA imaging for genetic analysis.

Using fixed fiduciary markers for stage drift correction.

Direct detection of adenosine in undiluted serum using a luminescent aptamer sensor attached to a terbium complex.

In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport.

Single-molecule fluorescence and in vivo optical traps: how multiple dyneins and kinesins interact.