Neurorestoration,
Wolfson Centre for Age-Related Diseases,
Neurorestoration, Wolfson Centre for Age-Related Diseases
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Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats.
Brain : a journal of neurology Sep, 2010 | Pubmed ID: 20802203
Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat.
PLoS biology , 2010 | Pubmed ID: 20585375
P2X receptors and their role in female idiopathic detrusor instability.
The Journal of urology Jan, 2002 | Pubmed ID: 11743296
Neurotrophin-3-mediated regeneration and recovery of proprioception following dorsal rhizotomy.
Molecular and cellular neurosciences Feb, 2002 | Pubmed ID: 11860276
Chondroitinase ABC promotes functional recovery after spinal cord injury.
Nature Apr, 2002 | Pubmed ID: 11948352
Molecular forms of NGF in human and rat neuropathic tissues: decreased NGF precursor-like immunoreactivity in human diabetic skin.
Journal of the peripheral nervous system : JPNS Sep, 2002 | Pubmed ID: 12365567
Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn.
Molecular and cellular neurosciences Dec, 2002 | Pubmed ID: 12504600
BDNF: a neuromodulator in nociceptive pathways?
Brain research. Brain research reviews Oct, 2002 | Pubmed ID: 12589922
EphB receptors and ephrin-B ligands regulate spinal sensory connectivity and modulate pain processing.
Nature neuroscience Apr, 2003 | Pubmed ID: 12640461
The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn.
Molecular and cellular neurosciences Oct, 2003 | Pubmed ID: 14572451
Glial cell line-derived neurotrophic factor increases calcitonin gene-related peptide immunoreactivity in sensory and motoneurons in vivo.
The European journal of neuroscience Nov, 2003 | Pubmed ID: 14656320
Ultraviolet radiation-induced inflammation as a model for cutaneous hyperalgesia.
The Journal of investigative dermatology Jan, 2004 | Pubmed ID: 14962107
NGF and GDNF ameliorate the increase in ATF3 expression which occurs in dorsal root ganglion cells in response to peripheral nerve injury.
The European journal of neuroscience Mar, 2004 | Pubmed ID: 15066140
Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2004 | Pubmed ID: 15128857
Plasticity of pain signaling: role of neurotrophic factors exemplified by acid-induced pain.
Journal of neurobiology Oct, 2004 | Pubmed ID: 15362154
Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord.
The European journal of neuroscience Oct, 2004 | Pubmed ID: 15379998
Neurotrophic influences on neuropathic pain.
Novartis Foundation symposium , 2004 | Pubmed ID: 15469045
Acid-induced pain and its modulation in humans.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2004 | Pubmed ID: 15574747
Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2005 | Pubmed ID: 15716400
Increased spinal cord phosphorylation of extracellular signal-regulated kinases mediates micturition overactivity in rats with chronic bladder inflammation.
The European journal of neuroscience Feb, 2005 | Pubmed ID: 15733095
Regulation of neuropilin 1 by spinal cord injury in adult rats.
Molecular and cellular neurosciences Mar, 2005 | Pubmed ID: 15737738
Immune and glial cell factors as pain mediators and modulators.
Experimental neurology Apr, 2005 | Pubmed ID: 15755561
Activity-dependent phosphorylation of Akt/PKB in adult DRG neurons.
The European journal of neuroscience Apr, 2005 | Pubmed ID: 15869474
P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP.
The Journal of physiology Sep, 2005 | Pubmed ID: 15961431
TrkB expression and phospho-ERK activation by brain-derived neurotrophic factor in rat spinothalamic tract neurons.
The Journal of comparative neurology Aug, 2005 | Pubmed ID: 15977164
Inhibition of ERK phosphorylation decreases nociceptive behaviour in monoarthritic rats.
Pain Aug, 2005 | Pubmed ID: 15979799
Role of the immune system in chronic pain.
Nature reviews. Neuroscience Jul, 2005 | Pubmed ID: 15995723
Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice.
Experimental neurology Oct, 2005 | Pubmed ID: 16051217
Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord.
Nature neuroscience Feb, 2006 | Pubmed ID: 16388307
Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain.
Molecular and cellular neurosciences Mar, 2006 | Pubmed ID: 16413788
ATF3 expression in L4 dorsal root ganglion neurons after L5 spinal nerve transection.
The European journal of neuroscience Jan, 2006 | Pubmed ID: 16420444
A clonal cell line from immortalized olfactory ensheathing glia promotes functional recovery in the injured spinal cord.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2006 | Pubmed ID: 16427362
Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2006 | Pubmed ID: 16504588
Spinal ERK activation contributes to the regulation of bladder function in spinal cord injured rats.
Experimental neurology Jul, 2006 | Pubmed ID: 16513110
Role of spinal microglia in rat models of peripheral nerve injury and inflammation.
European journal of pain (London, England) Feb, 2007 | Pubmed ID: 16545974
Increasingly irritable and close to tears: TRPA1 in inflammatory pain.
Cell Mar, 2006 | Pubmed ID: 16564004
Neurotrophins: mediators and modulators of pain.
Annual review of neuroscience , 2006 | Pubmed ID: 16776595
Spinal cord repair strategies: why do they work?
Nature reviews. Neuroscience Aug, 2006 | Pubmed ID: 16858392
Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammation.
Journal of neurochemistry Nov, 2006 | Pubmed ID: 16942597
Lentiviral vector expressing retinoic acid receptor beta2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord.
Human molecular genetics Nov, 2006 | Pubmed ID: 16984961
Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.
Molecular pain , 2006 | Pubmed ID: 17052333
Artemin has potent neurotrophic actions on injured C-fibres.
Journal of the peripheral nervous system : JPNS Dec, 2006 | Pubmed ID: 17117942
Pharmacological, behavioural and mechanistic analysis of HIV-1 gp120 induced painful neuropathy.
Pain Dec, 2007 | Pubmed ID: 17433546
The activation of the ERK pathway contributes to the spinal c-fos expression observed after noxious bladder stimulation.
Somatosensory & motor research Mar-Jun, 2007 | Pubmed ID: 17558919
Pathophysiology of peripheral neuropathic pain: immune cells and molecules.
Anesthesia and analgesia Sep, 2007 | Pubmed ID: 17717248
Characterization of rodent models of HIV-gp120 and anti-retroviral-associated neuropathic pain.
Brain : a journal of neurology Oct, 2007 | Pubmed ID: 17761732
Heritability of responses to painful stimuli in women: a classical twin study.
Brain : a journal of neurology Nov, 2007 | Pubmed ID: 17932101
Transplanted neural progenitor cells survive and differentiate but achieve limited functional recovery in the lesioned adult rat spinal cord.
Regenerative medicine Nov, 2007 | Pubmed ID: 18034631
Modulation of acid-sensing ion channel activity by nitric oxide.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2007 | Pubmed ID: 18045919
Microchannels as axonal amplifiers.
IEEE transactions on bio-medical engineering Mar, 2008 | Pubmed ID: 18334406
Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2008 | Pubmed ID: 18417706
CCL2 is a key mediator of microglia activation in neuropathic pain states.
European journal of pain (London, England) Mar, 2009 | Pubmed ID: 18554968
Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain.
European journal of pain (London, England) Apr, 2009 | Pubmed ID: 18606552
Ultraviolet-B induced inflammation of human skin: characterisation and comparison with traditional models of hyperalgesia.
European journal of pain (London, England) May, 2009 | Pubmed ID: 18691920
Mice lacking acid-sensing ion channels (ASIC) 1 or 2, but not ASIC3, show increased pain behaviour in the formalin test.
European journal of pain (London, England) Jul, 2009 | Pubmed ID: 18801682
Effects of Etanercept and Minocycline in a rat model of spinal cord injury.
European journal of pain (London, England) Aug, 2009 | Pubmed ID: 18849175
Chondroitinase ABC-mediated plasticity of spinal sensory function.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2008 | Pubmed ID: 19005065
Expression of the regeneration-associated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury.
The Journal of comparative neurology Mar, 2009 | Pubmed ID: 19107756
The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2008 | Pubmed ID: 19109493
Microchannel electrodes for recording and stimulation: in vitro evaluation.
IEEE transactions on bio-medical engineering May, 2009 | Pubmed ID: 19203882
Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2009 | Pubmed ID: 19535578
Future treatment strategies for neuropathic pain.
Handbook of experimental pharmacology , 2009 | Pubmed ID: 19655119
Current challenges in glia-pain biology.
Neuron Oct, 2009 | Pubmed ID: 19840548
Identification of perineal sensory neurons activated by innocuous heat.
The Journal of comparative neurology Jan, 2010 | Pubmed ID: 19937707
P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2010 | Pubmed ID: 20071520
Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2/3 receptors in the spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2010 | Pubmed ID: 20335487
Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation.
Pain Jul, 2010 | Pubmed ID: 20478657
Neural progenitors promote axon growth in vitro and ex vivo but not following injury.
Journal of stem cells , 2009 | Pubmed ID: 20498687
Delayed treatment with chondroitinase ABC reverses chronic atrophy of rubrospinal neurons following spinal cord injury.
Experimental neurology Mar, 2011 | Pubmed ID: 21215745
Perturbing PSD-95 interactions with NR2B-subtype receptors attenuates spinal nociceptive plasticity and neuropathic pain.
Molecular therapy : the journal of the American Society of Gene Therapy Oct, 2011 | Pubmed ID: 21427709
New molecules for the treatment of pain.
Current opinion in supportive and palliative care Jun, 2011 | Pubmed ID: 21455071
CXCL5 mediates UVB irradiation-induced pain.
Science translational medicine Jul, 2011 | Pubmed ID: 21734176
Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat.
Molecular pain , 2011 | Pubmed ID: 22054645
Conduction failure following spinal cord injury: functional and anatomical changes from acute to chronic stages.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2011 | Pubmed ID: 22171053
A regenerative microchannel neural interface for recording from and stimulating peripheral axons in vivo.
Journal of neural engineering Feb, 2012 | Pubmed ID: 22258138
Chronic pain: emerging evidence for the involvement of epigenetics.
Neuron Feb, 2012 | Pubmed ID: 22325197
Understanding chronic inflammatory and neuropathic pain.
Annals of the New York Academy of Sciences May, 2012 | Pubmed ID: 22564068
Chondroitinase ABC promotes plasticity of spinal reflexes following peripheral nerve injury.
Experimental neurology Nov, 2012 | Pubmed ID: 22917776
Sensory neuron downregulation of the Kv9.1 potassium channel subunit mediates neuropathic pain following nerve injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2012 | Pubmed ID: 23197740
Genes contributing to pain sensitivity in the normal population: an exome sequencing study.
PLoS genetics , 2012 | Pubmed ID: 23284290
Genes and epigenetic processes as prospective pain targets.
Genome medicine , 2013 | Pubmed ID: 23409739
Characterisation and mechanisms of bradykinin-evoked pain in man using iontophoresis.
Pain Jun, 2013 | Pubmed ID: 23422725
HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain.
Pain Sep, 2013 | Pubmed ID: 23693161
Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.
Brain : a journal of neurology Jul, 2013 | Pubmed ID: 23801741
Chronic cough and pain: Janus faces in sensory neurobiology?
Pulmonary pharmacology & therapeutics Oct, 2013 | Pubmed ID: 23831712
PainNetworks: a web-based resource for the visualisation of pain-related genes in the context of their network associations.
Pain Dec, 2013 | Pubmed ID: 24036287
Chemokines as peripheral pain mediators.
Neuroscience letters Dec, 2013 | Pubmed ID: 24120432
A microchannel neuroprosthesis for bladder control after spinal cord injury in rat.
Science translational medicine Nov, 2013 | Pubmed ID: 24197736
Chemokine expression in peripheral tissues from the monosodium iodoacetate model of chronic joint pain.
Molecular pain , 2013 | Pubmed ID: 24206615
Kv2 dysfunction after peripheral axotomy enhances sensory neuron responsiveness to sustained input.
Experimental neurology Jan, 2014 | Pubmed ID: 24252178
Probing functional properties of nociceptive axons using a microfluidic culture system.
PloS one , 2013 | Pubmed ID: 24278311
Synthesis of lipid mediators during UVB-induced inflammatory hyperalgesia in rats and mice.
PloS one , 2013 | Pubmed ID: 24349046
Opening paths to novel analgesics: the role of potassium channels in chronic pain.
Trends in neurosciences Mar, 2014 | Pubmed ID: 24461875
A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat.
Molecular pain , 2014 | Pubmed ID: 24472155
Pain vulnerability: a neurobiological perspective.
Nature neuroscience Feb, 2014 | Pubmed ID: 24473267
Botulinum toxin-A treatment reduces human mechanical pain sensitivity and mechanotransduction.
Annals of neurology Apr, 2014 | Pubmed ID: 24550077
Molecular mechanisms underlying the enhanced analgesic effect of oxycodone compared to morphine in chemotherapy-induced neuropathic pain.
PloS one , 2014 | Pubmed ID: 24618941
Genome-wide transcriptional profiling of skin and dorsal root ganglia after ultraviolet-B-induced inflammation.
PloS one , 2014 | Pubmed ID: 24732968
Null mutation in SCN9A in which noxious stimuli can be detected in the absence of pain.
Neurology Oct, 2014 | Pubmed ID: 25253744
Defining the nociceptor transcriptome.
Frontiers in molecular neuroscience , 2014 | Pubmed ID: 25426020
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