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Safety and immunogenicity of ALVAC vCP1452 and recombinant gp160 in newly human immunodeficiency virus type 1-infected patients treated with prolonged highly active antiretroviral therapy.
Journal of virology Mar, 2002 | Pubmed ID: 11836398
Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12244097
Alkylating DNA damage stimulates a regulated form of necrotic cell death.
Genes & development Jun, 2004 | Pubmed ID: 15145826
Akt stimulates aerobic glycolysis in cancer cells.
Cancer research Jun, 2004 | Pubmed ID: 15172999
Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2004 | Pubmed ID: 15180958
Growth factor regulation of autophagy and cell survival in the absence of apoptosis.
Cell Jan, 2005 | Pubmed ID: 15680329
The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation.
Oncogene Jun, 2005 | Pubmed ID: 15806154
ATP citrate lyase is an important component of cell growth and transformation.
Oncogene Sep, 2005 | Pubmed ID: 16007201
ATP citrate lyase inhibition can suppress tumor cell growth.
Cancer cell Oct, 2005 | Pubmed ID: 16226706
BRD4-NUT carcinoma of the mediastinum in a pediatric patient: multidetector computed tomography imaging findings.
Journal of thoracic imaging Aug, 2010 | Pubmed ID: 20395873
Update on fetal hemoglobin gene regulation in hemoglobinopathies.
Current opinion in pediatrics Feb, 2011 | Pubmed ID: 21157349
Differentiation of NUT midline carcinoma by epigenomic reprogramming.
Cancer research Apr, 2011 | Pubmed ID: 21447744
Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S.
American journal of physiology. Cell physiology Dec, 2011 | Pubmed ID: 21849667
Clinicopathologic features and long-term outcomes of NUT midline carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2012 | Pubmed ID: 22896655
Reawakening fetal hemoglobin: prospects for new therapies for the β-globin disorders.
Blood Oct, 2012 | Pubmed ID: 22904296
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.
Genes & development Sep, 2012 | Pubmed ID: 22929040
Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis.
Developmental cell Oct, 2012 | Pubmed ID: 23041383
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2013 | Pubmed ID: 23576758
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
Science (New York, N.Y.) Oct, 2013 | Pubmed ID: 24115442
Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.
The Journal of biological chemistry Aug, 2014 | Pubmed ID: 24907273
TMEM14C is required for erythroid mitochondrial heme metabolism.
The Journal of clinical investigation Oct, 2014 | Pubmed ID: 25157825
Harvard Medical School
Boston Children's Hospital
Dana-Farber Cancer Institute
Daniel E. Bauer*,1,2,3,
Matthew C. Canver*,1,
Stuart H. Orkin1,2,3,4
1, Harvard Medical School,
2Division of Hematology/Oncology, Boston Children's Hospital,
3Department of Pediatric Oncology, Dana-Farber Cancer Institute,
4, Howard Hughes Medical Institute
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