Department of Pharmacology and Toxicology
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Upregulation of arterial serotonin 1B and 2B receptors in deoxycorticosterone acetate-salt hypertension.
Hypertension Feb, 2002 | Pubmed ID: 11882579
Serotonin-induced contraction in mesenteric resistance arteries: signaling and changes in deoxycorticosterone acetate-salt hypertension.
Hypertension Mar, 2002 | Pubmed ID: 11897772
Endothelin receptor function in mesenteric veins from deoxycorticosterone acetate salt-hypertensive rats.
Journal of hypertension Apr, 2002 | Pubmed ID: 11910302
Endothelin-1-induced venous contraction is maintained in DOCA-salt hypertension; studies with receptor agonists.
British journal of pharmacology Sep, 2002 | Pubmed ID: 12183332
Phosphoinositide 3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of deoxycorticosterone acetate-salt hypertensive rats.
Circulation research Aug, 2002 | Pubmed ID: 12193470
5-Hydroxytryptamine(2B) receptor function is enhanced in the N(omega)-nitro-L-arginine hypertensive rat.
The Journal of pharmacology and experimental therapeutics Oct, 2002 | Pubmed ID: 12235249
Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension.
Circulation Feb, 2003 | Pubmed ID: 12600921
PI3-kinase-induced hyperreactivity in DOCA-salt hypertension is independent of GSK-3 activity.
Hypertension Apr, 2003 | Pubmed ID: 12629035
NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension.
Hypertension Sep, 2003 | Pubmed ID: 12885792
Arterial expression of 5-HT2B and 5-HT1B receptors during development of DOCA-salt hypertension.
BMC pharmacology Sep, 2003 | Pubmed ID: 12974983
Low [Mg2+]e enhances arterial spontaneous tone via phosphatidylinositol 3-kinase in DOCA-salt hypertension.
Hypertension Jan, 2004 | Pubmed ID: 14638620
Characterization of the contractile 5-hydroxytryptamine receptor in the renal artery of the normotensive rat.
The Journal of pharmacology and experimental therapeutics Apr, 2004 | Pubmed ID: 14724222
The fenfluramine metabolite (+)-norfenfluramine is vasoactive.
The Journal of pharmacology and experimental therapeutics May, 2004 | Pubmed ID: 14752059
Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension.
The Journal of pharmacology and experimental therapeutics Jun, 2004 | Pubmed ID: 14982964
PI3-kinase upregulation and involvement in spontaneous tone in arteries from DOCA-salt rats: is p110delta the culprit?
Hypertension Apr, 2004 | Pubmed ID: 14993194
Increased O2*- production and upregulation of ETB receptors by sympathetic neurons in DOCA-salt hypertensive rats.
Hypertension May, 2004 | Pubmed ID: 15051669
Arteries and veins desensitize differently to endothelin.
Journal of cardiovascular pharmacology Mar, 2004 | Pubmed ID: 15076222
Increased vascular sensitivity and connexin43 expression after sympathetic denervation.
Cardiovascular research May, 2004 | Pubmed ID: 15094358
C3 or not C3: that is the question.
Hypertension Jul, 2004 | Pubmed ID: 15123574
The serotonin transporter is present and functional in peripheral arterial smooth muscle.
Journal of cardiovascular pharmacology Jun, 2004 | Pubmed ID: 15167270
Effects of PPAR-gamma ligands on vascular smooth muscle marker expression in hypertensive and normal arteries.
American journal of physiology. Heart and circulatory physiology Jan, 2005 | Pubmed ID: 15345487
Endothelin in the splanchnic vascular bed of DOCA-salt hypertensive rats.
American journal of physiology. Heart and circulatory physiology Feb, 2005 | Pubmed ID: 15471983
Preserving and promoting our discipline: pharmacology students speak out.
Molecular interventions Feb, 2005 | Pubmed ID: 15731498
5-HT in systemic hypertension: foe, friend or fantasy?
Clinical science (London, England : 1979) May, 2005 | Pubmed ID: 15831089
(+)-Norfenfluramine-induced arterial contraction is not dependent on endogenous 5-hydroxytryptamine or 5-hydroxytryptamine transporter.
The Journal of pharmacology and experimental therapeutics Sep, 2005 | Pubmed ID: 15901794
Endothelin-1-induced contraction in veins is independent of hydrogen peroxide.
American journal of physiology. Heart and circulatory physiology Sep, 2005 | Pubmed ID: 15908460
Upregulated function of phosphatidylinositol-3-kinase in genetically hypertensive rats: a moderator of arterial hypercontractility.
Clinical and experimental pharmacology & physiology Oct, 2005 | Pubmed ID: 16173947
Activation of vascular BK channel by tempol in DOCA-salt hypertensive rats.
Hypertension Nov, 2005 | Pubmed ID: 16216988
Vasoconstriction caused by the ATP synthase subunit-coupling factor 6: a new function for a historical enzyme.
Hypertension Nov, 2005 | Pubmed ID: 16230522
Pleiotropic effects of hydrogen peroxide in arteries and veins from normotensive and hypertensive rats.
Hypertension Mar, 2006 | Pubmed ID: 16432037
Arterial 5-hydroxytryptamine transporter function is impaired in deoxycorticosterone acetate and Nomega-nitro-L-arginine but not spontaneously hypertensive rats.
Hypertension Jul, 2006 | Pubmed ID: 16754787
5-hydroxytryptamine in the cardiovascular system: focus on the serotonin transporter (SERT).
Clinical and experimental pharmacology & physiology Jul, 2006 | Pubmed ID: 16789923
Mechanisms of hypertension induced by nitric oxide (NO) deficiency: focus on venous function.
Journal of cardiovascular pharmacology Jun, 2006 | Pubmed ID: 16810074
A new signaling paradigm for serotonin: use of Crk-associated substrate in arterial contraction.
American journal of physiology. Heart and circulatory physiology Dec, 2006 | Pubmed ID: 16861698
Cyclooxygenase, p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase MAPK, Rho kinase, and Src mediate hydrogen peroxide-induced contraction of rat thoracic aorta and vena cava.
The Journal of pharmacology and experimental therapeutics Jan, 2007 | Pubmed ID: 17003231
A comparison of arteries and veins in oxidative stress: producers, destroyers, function, and disease.
Experimental biology and medicine (Maywood, N.J.) Jan, 2007 | Pubmed ID: 17202583
Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats.
American journal of physiology. Heart and circulatory physiology May, 2007 | Pubmed ID: 17237246
The 5-hydroxytryptamine2A receptor is involved in (+)-norfenfluramine-induced arterial contraction and blood pressure increase in deoxycorticosterone acetate-salt hypertension.
The Journal of pharmacology and experimental therapeutics May, 2007 | Pubmed ID: 17289838
Preferential myosin heavy chain isoform B Expression may contribute to the faster velocity of contraction in veins versus arteries.
Journal of vascular research , 2007 | Pubmed ID: 17377397
Methyl-beta-cyclodextrin prevents angiotensin II-induced tachyphylactic contractile responses in rat aorta.
The Journal of pharmacology and experimental therapeutics Oct, 2007 | Pubmed ID: 17636007
Serotonin (5-HT) in veins: not all in vain.
The Journal of pharmacology and experimental therapeutics Nov, 2007 | Pubmed ID: 17671100
The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta.
The Journal of pharmacology and experimental therapeutics Nov, 2007 | Pubmed ID: 17687070
Big ET-1 processing into vasoactive peptides in arteries and veins.
Vascular pharmacology Nov-Dec, 2007 | Pubmed ID: 17904426
Vascular reactivity, 5-HT uptake, and blood pressure in the serotonin transporter knockout rat.
American journal of physiology. Heart and circulatory physiology Apr, 2008 | Pubmed ID: 18263707
Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite.
Journal of vascular surgery Mar, 2008 | Pubmed ID: 18295111
5-Hydroxytryptamine lowers blood pressure in normotensive and hypertensive rats.
The Journal of pharmacology and experimental therapeutics Jun, 2008 | Pubmed ID: 18305011
A serotonergic system in veins: serotonin transporter-independent uptake.
The Journal of pharmacology and experimental therapeutics Jun, 2008 | Pubmed ID: 18322152
Pharmacological endothelin receptor interaction does not occur in veins from ET(B) receptor deficient rats.
Vascular pharmacology Jul, 2008 | Pubmed ID: 18485831
Lack of the serotonin transporter does not prevent mineralocorticoid hypertension in rat and mouse.
European journal of pharmacology Jul, 2008 | Pubmed ID: 18573249
A comparison of reactive oxygen species metabolism in the rat aorta and vena cava: focus on xanthine oxidase.
American journal of physiology. Heart and circulatory physiology Sep, 2008 | Pubmed ID: 18660442
The love of a lifetime: 5-HT in the cardiovascular system.
American journal of physiology. Regulatory, integrative and comparative physiology Feb, 2009 | Pubmed ID: 18753260
The beginning of a fantastic, unanswered question: is 5-HT involved in systemic hypertension?
American journal of physiology. Heart and circulatory physiology Sep, 2008 | Pubmed ID: 18775854
Body distribution of infused serotonin in rats.
Clinical and experimental pharmacology & physiology May, 2009 | Pubmed ID: 19207716
Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein.
The Journal of pharmacology and experimental therapeutics Jun, 2009 | Pubmed ID: 19297422
Serotonylation of vascular proteins important to contraction.
PloS one , 2009 | Pubmed ID: 19479059
Differential expression of pancreatitis-associated protein and thrombospondins in arterial versus venous tissues.
Journal of vascular research , 2009 | Pubmed ID: 19571575
Endothelin receptors: what's new and what do we need to know?
American journal of physiology. Regulatory, integrative and comparative physiology Feb, 2010 | Pubmed ID: 19907001
Uric acid does not affect the acetylcholine-induced relaxation of aorta from normotensive and deoxycorticosterone acetate-salt hypertensive rats.
The Journal of pharmacology and experimental therapeutics Jun, 2010 | Pubmed ID: 20215410
Whole grape intake impacts cardiac peroxisome proliferator-activated receptor and nuclear factor kappaB activity and cytokine expression in rats with diastolic dysfunction.
Hypertension May, 2010 | Pubmed ID: 20231522
Serotonin receptors in rat jugular vein: presence and involvement in the contraction.
The Journal of pharmacology and experimental therapeutics Jul, 2010 | Pubmed ID: 20378714
5-hydroxtryptamine receptors in systemic hypertension: an arterial focus.
Cardiovascular therapeutics Feb, 2011 | Pubmed ID: 20433685
The interdependence of endothelin-1 and calcium: a review.
Clinical science (London, England : 1979) Nov, 2010 | Pubmed ID: 20662769
Allopurinol does not decrease blood pressure or prevent the development of hypertension in the deoxycorticosterone acetate-salt rat model.
Journal of cardiovascular pharmacology Dec, 2010 | Pubmed ID: 20881613
Serotonin transporter interacts with the PDGFβ receptor in PDGF-BB-induced signaling and mitogenesis in pulmonary artery smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology Mar, 2011 | Pubmed ID: 21186266
Comparison of the function of the serotonin transporter in the vasculature of male and female rats.
Clinical and experimental pharmacology & physiology May, 2011 | Pubmed ID: 21371073
Characterization of vabicaserin (SCA-136), a selective 5-hydroxytryptamine 2C receptor agonist.
The Journal of pharmacology and experimental therapeutics Jun, 2011 | Pubmed ID: 21402690
Modification of proteins by norepinephrine is important for vascular contraction.
Frontiers in physiology , 2010 | Pubmed ID: 21423373
Lack of the serotonin transporter (SERT) reduces the ability of 5-hydroxytryptamine to lower blood pressure.
Naunyn-Schmiedeberg's archives of pharmacology May, 2011 | Pubmed ID: 21448568
Indoleamine 2,3-diooxygenase in periaortic fat: mechanisms of inhibition of contraction.
American journal of physiology. Heart and circulatory physiology Oct, 2011 | Pubmed ID: 21841011
Drug Delivery: Enabling Technology for Drug Discovery and Development. iPRECIO Micro Infusion Pump: Programmable, Refillable, and Implantable.
Frontiers in pharmacology , 2011 | Pubmed ID: 21863140
Vena Cava and Aortic Smooth Muscle Cells Express Transglutaminases 1 and 4 in addition to Transglutaminase 2.
American journal of physiology. Heart and circulatory physiology Feb, 2012 | Pubmed ID: 22307675
Smooth muscle pharmacology in the isolated virgin and pregnant rat uterus and cervix.
The Journal of pharmacology and experimental therapeutics Jun, 2012 | Pubmed ID: 22366660
Serotonin and blood pressure regulation.
Pharmacological reviews Apr, 2012 | Pubmed ID: 22407614
5-hydroxytryptamine (5-HT) reduces total peripheral resistance during chronic infusion: direct arterial mesenteric relaxation is not involved.
BMC pharmacology , 2012 | Pubmed ID: 22559843
Reverse-mode Na+/Ca2+ exchange is an important mediator of venous contraction.
Pharmacological research : the official journal of the Italian Pharmacological Society Dec, 2012 | Pubmed ID: 22974823
One-Month Serotonin Infusion Results in a Prolonged Fall in Blood Pressure in the Deoxycorticosterone Acetate (DOCA) Salt Hypertensive Rat.
ACS chemical neuroscience Jan, 2013 | Pubmed ID: 23336053
Long-Term Inhibition of Xanthine Oxidase by Febuxostat Does Not Decrease Blood Pressure in Deoxycorticosterone Acetate (DOCA)-Salt Hypertensive Rats.
PloS one , 2013 | Pubmed ID: 23393607
Chemerin connects fat to arterial contraction.
Arteriosclerosis, thrombosis, and vascular biology Jun, 2013 | Pubmed ID: 23559624
Divergent signaling mechanisms for venous versus arterial contraction as revealed by endothelin-1.
Journal of vascular surgery Apr, 2014 | Pubmed ID: 24726828
The persistence of active smooth muscle in the female rat cervix through pregnancy.
American journal of obstetrics and gynecology Aug, 2014 | Pubmed ID: 25108144
Serotonin and sensory nerves: meeting in the cardiovascular system.
Vascular pharmacology Oct, 2014 | Pubmed ID: 25181552
Elimination of vitamin D receptor in vascular endothelial cells alters vascular function.
Hypertension Dec, 2014 | Pubmed ID: 25201890
Tissue transglutaminase promotes serotonin-induced AKT signaling and mitogenesis in pulmonary vascular smooth muscle cells.
Cellular signalling Dec, 2014 | Pubmed ID: 25218191
Transglutaminase activity is decreased in large arteries from hypertensive rats compared with normotensive controls.
American journal of physiology. Heart and circulatory physiology Mar, 2015 | Pubmed ID: 25599570
5-HT is a potent relaxant in rat superior mesenteric veins.
Pharmacology research & perspectives Feb, 2015 | Pubmed ID: 25692021
5-Hydroxytryptamine does not reduce sympathetic nerve activity or neuroeffector function in the splanchnic circulation.
European journal of pharmacology May, 2015 | Pubmed ID: 25732865
Trash Talk by Fat: Chemerin as a Reactive Oxygen Species Provocateur in the Vasculature.
Hypertension (Dallas, Tex. : 1979) Sep, 2015 | Pubmed ID: 26150433
Chemerin: A comprehensive review elucidating the need for cardiovascular research.
Pharmacological research Sep, 2015 | Pubmed ID: 26211950
An immunohistochemical analysis of SERT in the blood-brain barrier of the male rat brain.
Histochemistry and cell biology Oct, 2015 | Pubmed ID: 26223876
Organic cation transporter 3 contributes to norepinephrine uptake into perivascular adipose tissue.
American journal of physiology. Heart and circulatory physiology Dec, 2015 | Pubmed ID: 26432838
Introducing a checklist for manuscript submission to Pharmacological Research.
Pharmacological research Dec, 2015 | Pubmed ID: 26523875
Pharmacological research and precision cancer medicine: A call for manuscripts.
Pharmacological research Dec, 2015 | Pubmed ID: 26542638
Serial Measurements of Splanchnic Vein Diameters in Rats Using High-Frequency Ultrasound.
Frontiers in pharmacology , 2016 | Pubmed ID: 27199758
The adipokine chemerin amplifies electrical field-stimulated contraction in the isolated rat superior mesenteric artery.
American journal of physiology. Heart and circulatory physiology Aug, 2016 | Pubmed ID: 27371688
Oh, the places you'll go! My many colored serotonin (apologies to Dr. Seuss).
American journal of physiology. Heart and circulatory physiology Nov, 2016 | Pubmed ID: 27663771
The distribution and adipogenic potential of perivascular adipose tissue adipocyte progenitors is dependent on sexual dimorphism and vessel location.
Physiological reports Oct, 2016 | Pubmed ID: 27738018
New actions of an old friend: perivascular adipose tissue's adrenergic mechanisms.
British journal of pharmacology Nov, 2016 | Pubmed ID: 27813085
Chemerin-induced arterial contraction is Gi- and calcium-dependent.
Vascular pharmacology Jan, 2017 | Pubmed ID: 27890480
3T3-L1 cells and perivascular adipocytes are not equivalent in amine transporter expression.
FEBS letters Jan, 2017 | Pubmed ID: 27926779
Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury.
The Journal of pharmacology and experimental therapeutics Mar, 2017 | Pubmed ID: 28035008
Perivascular Adipose Tissue's Impact on Norepinephrine-Induced Contraction of Mesenteric Resistance Arteries.
Frontiers in physiology , 2017 | Pubmed ID: 28228728
5-HT causes splanchnic venodilation.
American journal of physiology. Heart and circulatory physiology Jun, 2017 | Pubmed ID: 28626072
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