Department of Microbiology and Immunology
Roland Tisch has not added Biography.
If you are Roland Tisch and would like to personalize this page please email our Author Liaison for assistance.
Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2002 | Pubmed ID: 11751962
L-selectin is not required for T cell-mediated autoimmune diabetes.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2002 | Pubmed ID: 11884430
The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors.
European journal of immunology Dec, 2002 | Pubmed ID: 12516557
NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2003 | Pubmed ID: 12574341
More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2003 | Pubmed ID: 12817032
Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes.
Diabetes Sep, 2003 | Pubmed ID: 12941766
Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity.
Blood Aug, 2004 | Pubmed ID: 15113757
Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes.
The Journal of experimental medicine Apr, 2005 | Pubmed ID: 15837817
Immunoregulation of dendritic cells.
Clinical medicine & research Aug, 2005 | Pubmed ID: 16160071
Immunotherapy for the prevention and treatment of type 1 diabetes.
International reviews of immunology Sep-Dec, 2005 | Pubmed ID: 16318984
Low-avidity CD8lo T cells induced by incomplete antigen stimulation in vivo regulate naive higher avidity CD8hi T cell responses to the same antigen.
European journal of immunology Feb, 2006 | Pubmed ID: 16402405
Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2006 | Pubmed ID: 16424193
Lymphopenia-driven CD8(+) T cells are resistant to antigen-induced tolerance in NOD.scid mice.
European journal of immunology Aug, 2006 | Pubmed ID: 16821236
EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2006 | Pubmed ID: 16920914
Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells.
Blood Jan, 2007 | Pubmed ID: 17008547
Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2007 | Pubmed ID: 17237386
The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice.
Diabetes May, 2007 | Pubmed ID: 17317763
Alphaviral vector-transduced dendritic cells are successful therapeutic vaccines against neu-overexpressing tumors in wild-type mice.
Vaccine Sep, 2007 | Pubmed ID: 17675184
Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18093919
MerTK is required for apoptotic cell-induced T cell tolerance.
The Journal of experimental medicine Jan, 2008 | Pubmed ID: 18195070
B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2008 | Pubmed ID: 18292508
On the pathogenicity of autoantigen-specific T-cell receptors.
Diabetes May, 2008 | Pubmed ID: 18299317
T-cell promiscuity in autoimmune diabetes.
Diabetes Aug, 2008 | Pubmed ID: 18492786
Parameters influencing antigen-specific immunotherapy for type 1 diabetes.
Immunologic research , 2008 | Pubmed ID: 18543112
ANCA patients have T cells responsive to complementary PR-3 antigen.
Kidney international Nov, 2008 | Pubmed ID: 18596726
Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice.
Clinical immunology (Orlando, Fla.) Oct, 2008 | Pubmed ID: 18675592
Immunotherapy of type 1 diabetes.
Archivum immunologiae et therapiae experimentalis Jul-Aug, 2008 | Pubmed ID: 18726144
Parameters influencing antigen-specific immunotherapy for Type 1 diabetes.
Immunologic research , 2008 | Pubmed ID: 19052699
Role of plasmacytoid dendritic cells in type 1 diabetes: friend or foe?
Diabetes Jan, 2009 | Pubmed ID: 19114722
MerTK regulates thymic selection of autoreactive T cells.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2009 | Pubmed ID: 19251650
Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo.
Journal of virology Jul, 2009 | Pubmed ID: 19369348
Cellular immune response to cryptic epitopes during therapeutic gene transfer.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2009 | Pubmed ID: 19541644
CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice.
European journal of immunology Oct, 2009 | Pubmed ID: 19658094
A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells.
Blood Oct, 2009 | Pubmed ID: 19667404
Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2009 | Pubmed ID: 19752238
Islet lymphocyte subsets in male and female NOD mice are qualitatively similar but quantitatively distinct.
Autoimmunity , 2009 | Pubmed ID: 19886740
beta cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2009 | Pubmed ID: 19917704
Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2010 | Pubmed ID: 20220085
Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) May, 2010 | Pubmed ID: 20348424
Immunogenic versus tolerogenic dendritic cells: a matter of maturation.
International reviews of immunology Apr, 2010 | Pubmed ID: 20367138
Adiponectin lowers glucose production by increasing SOGA.
The American journal of pathology Oct, 2010 | Pubmed ID: 20813965
Dysregulation of thymic clonal deletion and the escape of autoreactive T cells.
Archivum immunologiae et therapiae experimentalis Dec, 2010 | Pubmed ID: 20872284
Genetic vaccination for re-establishing T-cell tolerance in type 1 diabetes.
Human vaccines Jan, 2011 | Pubmed ID: 21157183
Inducible adeno-associated virus-mediated IL-2 gene therapy prevents autoimmune diabetes.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2011 | Pubmed ID: 21317396
Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity.
European journal of immunology May, 2011 | Pubmed ID: 21469091
Cumulative autoimmunity: T cell clones recognizing several self-epitopes exhibit enhanced pathogenicity.
Frontiers in immunology , 2011 | Pubmed ID: 22566837
Long-term remission of diabetes in NOD mice is induced by nondepleting anti-CD4 and anti-CD8 antibodies.
Diabetes Nov, 2012 | Pubmed ID: 22751694
IFN-γ receptor deficiency prevents diabetes induction by diabetogenic CD4+, but not CD8+, T cells.
European journal of immunology Aug, 2012 | Pubmed ID: 22865049
Autoreactive effector/memory CD4+ and CD8+ T cells infiltrating grafted and endogenous islets in diabetic NOD mice exhibit similar T cell receptor usage.
PloS one , 2012 | Pubmed ID: 23251685
Kinetics of adeno-associated virus serotype 2 (AAV2) and AAV8 capsid antigen presentation in vivo are identical.
Human gene therapy May, 2013 | Pubmed ID: 23534873
Manipulating T cell-mediated pathology: targets and functions of monoclonal antibody immunotherapy.
Clinical immunology (Orlando, Fla.) Jul, 2013 | Pubmed ID: 23688653
β-cell-specific IL-2 therapy increases islet Foxp3+Treg and suppresses type 1 diabetes in NOD mice.
Diabetes Nov, 2013 | Pubmed ID: 23884888
Thymic development of autoreactive T cells in NOD mice is regulated in an age-dependent manner.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2013 | Pubmed ID: 24198282
Cutting edge: Antigen-specific thymocyte feedback regulates homeostatic thymic conventional dendritic cell maturation.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2014 | Pubmed ID: 24890722
IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2014 | Pubmed ID: 25063876
Reestablishing T Cell Tolerance by Antibody-Based Therapy in Type 1 Diabetes.
Archivum immunologiae et therapiae experimentalis Mar, 2015 | Pubmed ID: 25790749
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados