Department of Microbiology and Immunology
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Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2002 | Pubmed ID: 11751962
L-selectin is not required for T cell-mediated autoimmune diabetes.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2002 | Pubmed ID: 11884430
The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors.
European journal of immunology Dec, 2002 | Pubmed ID: 12516557
NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2003 | Pubmed ID: 12574341
More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2003 | Pubmed ID: 12817032
Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes.
Diabetes Sep, 2003 | Pubmed ID: 12941766
Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity.
Blood Aug, 2004 | Pubmed ID: 15113757
Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes.
The Journal of experimental medicine Apr, 2005 | Pubmed ID: 15837817
Immunoregulation of dendritic cells.
Clinical medicine & research Aug, 2005 | Pubmed ID: 16160071
Immunotherapy for the prevention and treatment of type 1 diabetes.
International reviews of immunology Sep-Dec, 2005 | Pubmed ID: 16318984
Low-avidity CD8lo T cells induced by incomplete antigen stimulation in vivo regulate naive higher avidity CD8hi T cell responses to the same antigen.
European journal of immunology Feb, 2006 | Pubmed ID: 16402405
Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2006 | Pubmed ID: 16424193
Lymphopenia-driven CD8(+) T cells are resistant to antigen-induced tolerance in NOD.scid mice.
European journal of immunology Aug, 2006 | Pubmed ID: 16821236
EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2006 | Pubmed ID: 16920914
Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells.
Blood Jan, 2007 | Pubmed ID: 17008547
Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2007 | Pubmed ID: 17237386
The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice.
Diabetes May, 2007 | Pubmed ID: 17317763
Alphaviral vector-transduced dendritic cells are successful therapeutic vaccines against neu-overexpressing tumors in wild-type mice.
Vaccine Sep, 2007 | Pubmed ID: 17675184
Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18093919
MerTK is required for apoptotic cell-induced T cell tolerance.
The Journal of experimental medicine Jan, 2008 | Pubmed ID: 18195070
B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2008 | Pubmed ID: 18292508
On the pathogenicity of autoantigen-specific T-cell receptors.
Diabetes May, 2008 | Pubmed ID: 18299317
T-cell promiscuity in autoimmune diabetes.
Diabetes Aug, 2008 | Pubmed ID: 18492786
Parameters influencing antigen-specific immunotherapy for type 1 diabetes.
Immunologic research , 2008 | Pubmed ID: 18543112
ANCA patients have T cells responsive to complementary PR-3 antigen.
Kidney international Nov, 2008 | Pubmed ID: 18596726
Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice.
Clinical immunology (Orlando, Fla.) Oct, 2008 | Pubmed ID: 18675592
Immunotherapy of type 1 diabetes.
Archivum immunologiae et therapiae experimentalis Jul-Aug, 2008 | Pubmed ID: 18726144
Parameters influencing antigen-specific immunotherapy for Type 1 diabetes.
Immunologic research , 2008 | Pubmed ID: 19052699
Role of plasmacytoid dendritic cells in type 1 diabetes: friend or foe?
Diabetes Jan, 2009 | Pubmed ID: 19114722
MerTK regulates thymic selection of autoreactive T cells.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2009 | Pubmed ID: 19251650
Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo.
Journal of virology Jul, 2009 | Pubmed ID: 19369348
Cellular immune response to cryptic epitopes during therapeutic gene transfer.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2009 | Pubmed ID: 19541644
CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice.
European journal of immunology Oct, 2009 | Pubmed ID: 19658094
A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells.
Blood Oct, 2009 | Pubmed ID: 19667404
Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2009 | Pubmed ID: 19752238
Islet lymphocyte subsets in male and female NOD mice are qualitatively similar but quantitatively distinct.
Autoimmunity , 2009 | Pubmed ID: 19886740
beta cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2009 | Pubmed ID: 19917704
Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2010 | Pubmed ID: 20220085
Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) May, 2010 | Pubmed ID: 20348424
Immunogenic versus tolerogenic dendritic cells: a matter of maturation.
International reviews of immunology Apr, 2010 | Pubmed ID: 20367138
Adiponectin lowers glucose production by increasing SOGA.
The American journal of pathology Oct, 2010 | Pubmed ID: 20813965
Dysregulation of thymic clonal deletion and the escape of autoreactive T cells.
Archivum immunologiae et therapiae experimentalis Dec, 2010 | Pubmed ID: 20872284
Genetic vaccination for re-establishing T-cell tolerance in type 1 diabetes.
Human vaccines Jan, 2011 | Pubmed ID: 21157183
Inducible adeno-associated virus-mediated IL-2 gene therapy prevents autoimmune diabetes.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2011 | Pubmed ID: 21317396
Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity.
European journal of immunology May, 2011 | Pubmed ID: 21469091
Cumulative autoimmunity: T cell clones recognizing several self-epitopes exhibit enhanced pathogenicity.
Frontiers in immunology , 2011 | Pubmed ID: 22566837
Long-term remission of diabetes in NOD mice is induced by nondepleting anti-CD4 and anti-CD8 antibodies.
Diabetes Nov, 2012 | Pubmed ID: 22751694
IFN-γ receptor deficiency prevents diabetes induction by diabetogenic CD4+, but not CD8+, T cells.
European journal of immunology Aug, 2012 | Pubmed ID: 22865049
Autoreactive effector/memory CD4+ and CD8+ T cells infiltrating grafted and endogenous islets in diabetic NOD mice exhibit similar T cell receptor usage.
PloS one , 2012 | Pubmed ID: 23251685
Kinetics of adeno-associated virus serotype 2 (AAV2) and AAV8 capsid antigen presentation in vivo are identical.
Human gene therapy May, 2013 | Pubmed ID: 23534873
Manipulating T cell-mediated pathology: targets and functions of monoclonal antibody immunotherapy.
Clinical immunology (Orlando, Fla.) Jul, 2013 | Pubmed ID: 23688653
β-cell-specific IL-2 therapy increases islet Foxp3+Treg and suppresses type 1 diabetes in NOD mice.
Diabetes Nov, 2013 | Pubmed ID: 23884888
Thymic development of autoreactive T cells in NOD mice is regulated in an age-dependent manner.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2013 | Pubmed ID: 24198282
Cutting edge: Antigen-specific thymocyte feedback regulates homeostatic thymic conventional dendritic cell maturation.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2014 | Pubmed ID: 24890722
IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2014 | Pubmed ID: 25063876
Reestablishing T Cell Tolerance by Antibody-Based Therapy in Type 1 Diabetes.
Archivum immunologiae et therapiae experimentalis Mar, 2015 | Pubmed ID: 25790749
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