School of Pharmacy
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NO attenuates insulin signaling and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B-mediated mechanism.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2002 | Pubmed ID: 12117721
Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho.
Circulation research Sep, 2002 | Pubmed ID: 12215487
Protein-tyrosine phosphatase-1B (PTP1B) mediates the anti-migratory actions of Sprouty.
The Journal of biological chemistry Jan, 2003 | Pubmed ID: 12414790
A newly synthetic chromium complex--chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance.
FEBS letters Feb, 2005 | Pubmed ID: 15733857
Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification.
Aging cell Apr, 2005 | Pubmed ID: 15771609
Views from within and beyond: narratives of cardiac contractile dysfunction under senescence.
Endocrine Mar, 2005 | Pubmed ID: 15888924
Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2006 | Pubmed ID: 16239599
Insulin-sensitizing and cholesterol-lowering effects of chromium (D-Phenylalanine)3.
Journal of inorganic biochemistry Jul, 2006 | Pubmed ID: 16545457
Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2006 | Pubmed ID: 16585059
Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt.
Aging cell Apr, 2006 | Pubmed ID: 16626396
Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme.
Free radical biology & medicine Apr, 2006 | Pubmed ID: 16631532
Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
Experimental neurology Jan, 2007 | Pubmed ID: 16962100
Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis.
Diabetes Sep, 2007 | Pubmed ID: 17575086
Impact of insulin-like growth factor-I on migration, proliferation and Akt-ERK signaling in early and late-passages of vascular smooth muscle cells.
Cardiovascular toxicology , 2007 | Pubmed ID: 17960499
Insulin-like growth factor I deficiency prolongs survival and antagonizes paraquat-induced cardiomyocyte dysfunction: role of oxidative stress.
Rejuvenation research Dec, 2007 | Pubmed ID: 17979500
Chromium (D-phenylalanine)3 improves obesity-induced cardiac contractile defect in ob/ob mice.
Obesity (Silver Spring, Md.) Nov, 2007 | Pubmed ID: 18070761
IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction.
American journal of physiology. Regulatory, integrative and comparative physiology Mar, 2008 | Pubmed ID: 18199585
Isolation and functional studies of rat aortic smooth muscle cells.
Methods in molecular medicine , 2007 | Pubmed ID: 18287680
Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice.
Obesity (Silver Spring, Md.) Jun, 2008 | Pubmed ID: 18388893
Antioxidant properties of argpyrimidine.
European journal of pharmacology Sep, 2008 | Pubmed ID: 18692042
Chromium (D-phenylalanine)3 supplementation alters glucose disposal, insulin signaling, and glucose transporter-4 membrane translocation in insulin-resistant mice.
The Journal of nutrition Oct, 2008 | Pubmed ID: 18806091
Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function.
Journal of cardiovascular pharmacology Nov, 2008 | Pubmed ID: 19033821
Chromium supplement inhibits skeletal muscle atrophy in hindlimb-suspended mice.
The Journal of nutritional biochemistry Dec, 2009 | Pubmed ID: 19071005
A newly synthetic chromium complex-chromium (D-phenylalanine)3 activates AMP-activated protein kinase and stimulates glucose transport.
Biochemical pharmacology Mar, 2009 | Pubmed ID: 19073152
2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities.
Biochemical pharmacology Feb, 2010 | Pubmed ID: 19769946
Tauroursodeoxycholic acid attenuates lipid accumulation in endoplasmic reticulum-stressed macrophages.
Journal of cardiovascular pharmacology Jan, 2010 | Pubmed ID: 19834331
AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of beta-catenin at Ser 552.
Biochemical and biophysical research communications Apr, 2010 | Pubmed ID: 20361929
Safety and toxicological evaluation of a novel chromium(III) dinicocysteinate complex.
Toxicology mechanisms and methods Jul, 2010 | Pubmed ID: 20515439
Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction.
Journal of molecular and cellular cardiology Jan, 2011 | Pubmed ID: 21035453
Chromium (D-phenylalanine)3 alleviates high fat-induced insulin resistance and lipid abnormalities.
Journal of inorganic biochemistry Jan, 2011 | Pubmed ID: 21134603
Overcoming cisplatin resistance using gold(III) mimics: anticancer activity of novel gold(III) polypyridyl complexes.
Journal of inorganic biochemistry Jan, 2012 | Pubmed ID: 22112837
Molecular mechanisms of chromium in alleviating insulin resistance.
The Journal of nutritional biochemistry Apr, 2012 | Pubmed ID: 22423897
Autophagy and cardiovascular aging: lesson learned from rapamycin.
Cell cycle (Georgetown, Tex.) Jun, 2012 | Pubmed ID: 22580468
Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction.
Diabetes Feb, 2013 | Pubmed ID: 23069627
Akt2 knockout preserves cardiac function in high-fat diet-induced obesity by rescuing cardiac autophagosome maturation.
Journal of molecular cell biology Feb, 2013 | Pubmed ID: 23258696
Cardiomyocyte-specific deletion of endothelin receptor A rescues aging-associated cardiac hypertrophy and contractile dysfunction: role of autophagy.
Basic research in cardiology Mar, 2013 | Pubmed ID: 23381122
Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3β-dependent inhibition of apoptosis and ER stress.
Biochimica et biophysica acta Jun, 2013 | Pubmed ID: 23474308
Cathepsin K knockout alleviates pressure overload-induced cardiac hypertrophy.
Hypertension Jun, 2013 | Pubmed ID: 23529168
Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation.
Molecular nutrition & food research Sep, 2013 | Pubmed ID: 23554078
Apelin administration ameliorates high fat diet-induced cardiac hypertrophy and contractile dysfunction.
Journal of molecular and cellular cardiology Jul, 2013 | Pubmed ID: 23859766
Influence of gestational overfeeding on myocardial proinflammatory mediators in fetal sheep heart.
The Journal of nutritional biochemistry Nov, 2013 | Pubmed ID: 24075902
Protein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.
PloS one , 2013 | Pubmed ID: 24204775
Macrophage migration inhibitory factor deletion exacerbates pressure overload-induced cardiac hypertrophy through mitigating autophagy.
Hypertension Mar, 2014 | Pubmed ID: 24366076
Novel curcumin derivative CNB-001 mitigates obesity-associated insulin resistance.
The Journal of pharmacology and experimental therapeutics May, 2014 | Pubmed ID: 24549372
Proteases in cardiometabolic diseases: Pathophysiology, molecular mechanisms and clinical applications.
Biochimica et biophysica acta Feb, 2015 | Pubmed ID: 24815358
Neuronostatin attenuates myocardial contractile function through inhibition of sarcoplasmic reticulum Ca2+-ATPase in murine heart.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology , 2014 | Pubmed ID: 25012062
Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: Role of AMPK-dependent autophagy.
Biochimica et biophysica acta Feb, 2015 | Pubmed ID: 25018087
AMP-activated protein kinase deficiency rescues paraquat-induced cardiac contractile dysfunction through an autophagy-dependent mechanism.
Toxicological sciences : an official journal of the Society of Toxicology Nov, 2014 | Pubmed ID: 25092649
Contribution of ALDH2 polymorphism to alcoholism-associated hypertension.
Recent patents on endocrine, metabolic & immune drug discovery , 2014 | Pubmed ID: 25354396
Cathepsin K knockout alleviates aging-induced cardiac dysfunction.
Aging cell Jun, 2015 | Pubmed ID: 25692548
Antioxidant Metallothionein Alleviates Endoplasmic Reticulum Stress-Induced Myocardial Apoptosis and Contractile Dysfunction.
Free radical research May, 2015 | Pubmed ID: 25968954
Jodi R. Schilz1,
K. J. Reddy2,
Sreejayan Nair3,
Thomas E. Johnson4,
Ronald B. Tjalkens5,
Kem P. Krueger3,
Suzanne Clark6
1Division of Physical Therapy, Department of Orthopedics & Rehabilitation, University of New Mexico,
2Department of Ecosystem Science and Management, University of Wyoming,
3School of Pharmacy, University of Wyoming,
4Department of Environmental and Radiological Health Sciences, Colorado State University,
5Center for Environmental Medicine, Colorado State University,
6College of Pharmacy, California Northstate University
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