Sreejayan Nair

NO attenuates insulin signaling and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B-mediated mechanism.

Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho.

Protein-tyrosine phosphatase-1B (PTP1B) mediates the anti-migratory actions of Sprouty.

A newly synthetic chromium complex--chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance.

Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification.

Views from within and beyond: narratives of cardiac contractile dysfunction under senescence.

Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation.

Insulin-sensitizing and cholesterol-lowering effects of chromium (D-Phenylalanine)3.

Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress.

Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt.

Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme.

Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.

Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis.

Impact of insulin-like growth factor-I on migration, proliferation and Akt-ERK signaling in early and late-passages of vascular smooth muscle cells.

Insulin-like growth factor I deficiency prolongs survival and antagonizes paraquat-induced cardiomyocyte dysfunction: role of oxidative stress.

Chromium (D-phenylalanine)3 improves obesity-induced cardiac contractile defect in ob/ob mice.

IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction.

Isolation and functional studies of rat aortic smooth muscle cells.

Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice.

Antioxidant properties of argpyrimidine.

Chromium (D-phenylalanine)3 supplementation alters glucose disposal, insulin signaling, and glucose transporter-4 membrane translocation in insulin-resistant mice.

Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function.

Chromium supplement inhibits skeletal muscle atrophy in hindlimb-suspended mice.

A newly synthetic chromium complex-chromium (D-phenylalanine)3 activates AMP-activated protein kinase and stimulates glucose transport.

2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities.

Tauroursodeoxycholic acid attenuates lipid accumulation in endoplasmic reticulum-stressed macrophages.

AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of beta-catenin at Ser 552.

Safety and toxicological evaluation of a novel chromium(III) dinicocysteinate complex.

Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction.

Chromium (D-phenylalanine)3 alleviates high fat-induced insulin resistance and lipid abnormalities.

Overcoming cisplatin resistance using gold(III) mimics: anticancer activity of novel gold(III) polypyridyl complexes.

Molecular mechanisms of chromium in alleviating insulin resistance.

Autophagy and cardiovascular aging: lesson learned from rapamycin.

Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction.

Akt2 knockout preserves cardiac function in high-fat diet-induced obesity by rescuing cardiac autophagosome maturation.

Cardiomyocyte-specific deletion of endothelin receptor A rescues aging-associated cardiac hypertrophy and contractile dysfunction: role of autophagy.

Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3β-dependent inhibition of apoptosis and ER stress.

Cathepsin K knockout alleviates pressure overload-induced cardiac hypertrophy.

Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation.

Apelin administration ameliorates high fat diet-induced cardiac hypertrophy and contractile dysfunction.

Influence of gestational overfeeding on myocardial proinflammatory mediators in fetal sheep heart.

Protein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.

Macrophage migration inhibitory factor deletion exacerbates pressure overload-induced cardiac hypertrophy through mitigating autophagy.

Novel curcumin derivative CNB-001 mitigates obesity-associated insulin resistance.

Proteases in cardiometabolic diseases: Pathophysiology, molecular mechanisms and clinical applications.

Neuronostatin attenuates myocardial contractile function through inhibition of sarcoplasmic reticulum Ca2+-ATPase in murine heart.

Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: Role of AMPK-dependent autophagy.

AMP-activated protein kinase deficiency rescues paraquat-induced cardiac contractile dysfunction through an autophagy-dependent mechanism.

Contribution of ALDH2 polymorphism to alcoholism-associated hypertension.

Cathepsin K knockout alleviates aging-induced cardiac dysfunction.

Antioxidant Metallothionein Alleviates Endoplasmic Reticulum Stress-Induced Myocardial Apoptosis and Contractile Dysfunction.