Asma Nusrat

Leukocyte transendothelial migration: a junctional affair.

Neutrophil transepithelial migration: evidence for sequential, contact-dependent signaling events and enhanced paracellular permeability independent of transjunctional migration.

The role of endothelial cell lateral junctions during leukocyte trafficking.

Expression of claudin-1, a recently described tight junction-associated protein, distinguishes soft tissue perineurioma from potential mimics.

Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function.

Zonula occludens-1 and Her-2/neu expression in invasive breast carcinoma.

Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment.

Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms.

Aberrant expression of tight junction-related proteins ZO-1, claudin-1 and occludin in synovial sarcoma: an immunohistochemical study with ultrastructural correlation.

RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin.

Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex.

ICAM-1: targeted docking for exogenous as well as endogenous ligands.

Epithelial cell spreading induced by hepatocyte growth factor influences paxillin protein synthesis and posttranslational modification.

JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration.

Association of BAP31 with CD11b/CD18. Potential role in intracellular trafficking of CD11b/CD18 in neutrophils.

Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigration.

Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin.

The epithelium in inflammatory bowel disease: potential role of endocytosis of junctional proteins in barrier disruption.

Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on beta1 integrins and Rap1 activity.

Citrobacter rodentium lifA/efa1 is essential for colonic colonization and crypt cell hyperplasia in vivo.

Endocytosis of the apical junctional complex: mechanisms and possible roles in regulation of epithelial barriers.

Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex.

Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils.

The second loop of occludin is required for suppression of Raf1-induced tumor growth.

Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like process.

Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane.

Interferon-gamma inhibits T84 epithelial cell migration by redirecting transcytosis of beta1 integrin from the migrating leading edge.

Regulation of the intestinal epithelial barrier by the apical junctional complex.

Microtubules regulate disassembly of epithelial apical junctions.

Plasmid DNA and siRNA transfection of intestinal epithelial monolayers by electroporation.

Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors.

Tight junctions and cell-cell interactions.

Inflammatory bowel disease and the apical junctional complex.

Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors.

Annexin 2 regulates intestinal epithelial cell spreading and wound closure through Rho-related signaling.

Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions.

Invasive Escherichia coli are a feature of Crohn's disease.

A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions.

Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium.

JAM-A regulates permeability and inflammation in the intestine in vivo.

Formyl peptide receptor-1 activation enhances intestinal epithelial cell restitution through phosphatidylinositol 3-kinase-dependent activation of Rac1 and Cdc42.

Role of the intestinal barrier in inflammatory bowel disease.

Cis-dimerization mediates function of junctional adhesion molecule A.

A key claudin extracellular loop domain is critical for epithelial barrier integrity.

Vesicular trafficking: molecular tools and targets.

Myosin II regulates the shape of three-dimensional intestinal epithelial cysts.

Lipid rafts mediate internalization of beta1-integrin in migrating intestinal epithelial cells.

Annexin A1 regulates intestinal mucosal injury, inflammation, and repair.

Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration.

Cytokine regulation of tight junctions.

Flotillin-1 stabilizes caveolin-1 in intestinal epithelial cells.

Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion.

Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration.

Pathophysiology of nasal polyposis: the role of desmosomal junctions.

Regulation of epithelial apical junctional complex by Rho family GTPases.

The bacterial virulence factor lymphostatin compromises intestinal epithelial barrier function by modulating rho GTPases.

Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility.

Dynamic regulation of epithelial cell fate and barrier function by intercellular junctions.

Dkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cells.

Coronin 1C negatively regulates cell-matrix adhesion and motility of intestinal epithelial cells.

Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.

Epithelial NF-kappaB enhances transmucosal fluid movement by altering tight junction protein composition after T cell activation.

Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways.

Cytoskeletal regulation of epithelial barrier function during inflammation.

Glycogen Synthase Kinase 3 (GSK-3) influences epithelial barrier function by regulating occludin, claudin-1 and E-cadherin expression.

Neutrophil migration across intestinal epithelium: evidence for a role of CD44 in regulating detachment of migrating cells from the luminal surface.

Commensal-epithelial signaling mediated via formyl peptide receptors.

Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling.

JAM-A regulates epithelial proliferation through Akt/β-catenin signalling.

Tight function zonula occludens-3 regulates cyclin D1-dependent cell proliferation.

The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.

Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases.

Characterization of full-length and proteolytic cleavage fragments of desmoglein-2 in native human colon and colonic epithelial cell lines.

Krüppel-like factor 5 is important for maintenance of crypt architecture and barrier function in mouse intestine.

The life and death of epithelia during inflammation: lessons learned from the gut.

Enteric commensal bacteria induce extracellular signal-regulated kinase pathway signaling via formyl peptide receptor-dependent redox modulation of dual specific phosphatase 3.

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice.

SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells.

Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function.

Epithelial tight junction alterations in nasal polyposis.

Regulation of epithelial proliferation by tight junction proteins.

Epithelial permeability alterations in an in vitro air-liquid interface model of allergic fungal rhinosinusitis.

Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis.

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair.

Activation of PKCβII by PMA facilitates enhanced epithelial wound repair through increased cell spreading and migration.

Challenges in IBD Research: Update on Progress and Prioritization of the CCFA's Research Agenda.

Sinonasal epithelial wound resealing in an in vitro model: inhibition of wound closure with IL-4 exposure.

Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure.

Annexin A2 regulates β1 integrin internalization and intestinal epithelial cell migration.

House dust mite allergen Der p 1 effects on sinonasal epithelial tight junctions.

The N-BAR domain protein, Bin3, regulates Rac1- and Cdc42-dependent processes in myogenesis.

JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.

α3/4 Fucosyltransferase 3-dependent synthesis of Sialyl Lewis A on CD44 variant containing exon 6 mediates polymorphonuclear leukocyte detachment from intestinal epithelium during transepithelial migration.

Tumor necrosis factor-neuropeptide Y cross talk regulates inflammation, epithelial barrier functions, and colonic motility.

Gut commensal bacteria and regional Wnt gene expression in the proximal versus distal colon.

Interleukin-4 and interleukin-13 compromise the sinonasal epithelial barrier and perturb intercellular junction protein expression.

Galectin-3 regulates desmoglein-2 and intestinal epithelial intercellular adhesion.

Epithelial adhesive junctions.

Cleavage of transmembrane junction proteins and their role in regulating epithelial homeostasis.

JAM-related proteins in mucosal homeostasis and inflammation.

Trans-dimerization of JAM-A regulates Rap2 and is mediated by a domain that is distinct from the cis-dimerization interface.

Crohn's disease-associated Escherichia coli survive in macrophages by suppressing NFκB signaling.

Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins.

Periostin and receptor activator of nuclear factor κ-B ligand expression in allergic fungal rhinosinusitis.

IFNγ-induced suppression of β-catenin signaling: evidence for roles of Akt and 14.3.3ζ.

Immunohistological characterization of intercellular junction proteins in rhesus macaque intestine.

RhoGTPases, actomyosin signaling and regulation of the epithelial Apical Junctional Complex.

Human neutrophil formyl peptide receptor phosphorylation and the mucosal inflammatory response.

Junctional adhesion molecule A promotes epithelial tight junction assembly to augment lung barrier function.

Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.

Introduction for the special issue on "Tissue Barriers in Inflammation".

Claudin switching: Physiological plasticity of the Tight Junction.

HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation.

Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier.

Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage.

Annexin A1: shifting the balance towards resolution and repair.

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol.

Redox control of Cas phosphorylation requires Abl kinase in regulation of intestinal epithelial cell spreading and migration.

Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair.

Pharmacological Targeting of the Inflamed Intestinal Barrier.

Deposition of microparticles by neutrophils onto inflamed epithelium: a new mechanism to disrupt epithelial intercellular adhesions and promote transepithelial migration.

The microenvironment of injured murine gut elicits a local pro-restitutive microbiota.

Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-α cascades.

IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria.

Overexpressed Claudin-1 Can Be Visualized Endoscopically in Colonic Adenomas In Vivo.

Cosmc is an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk.

IL-36γ signaling controls the induced regulatory T cell-Th9 cell balance via NFκB activation and STAT transcription factors.

Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation.

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.

Synthetic hydrogels for human intestinal organoid generation and colonic wound repair.

Indian Hedgehog Suppresses Intestinal Inflammation.

Serum Amyloid A1 Is an Epithelial Prorestitutive Factor.

Intracellular Desmoglein-2 cleavage sensitizes epithelial cells to apoptosis in response to pro-inflammatory cytokines.

A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage.

Cadherins: cellular adhesive molecules serving as signalling mediators.

PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery.

Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model.

Contribution of Wound-Associated Cells and Mediators in Orchestrating Gastrointestinal Mucosal Wound Repair.

Publisher Correction: PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery.

Role of JAM-A tyrosine phosphorylation in epithelial barrier dysfunction during intestinal inflammation.

Saving Problematic Mucosae: SPMs in Intestinal Mucosal Inflammation and Repair.

IL-10 produced by macrophages regulates epithelial integrity in the small intestine.

Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice.

Interactions Between Commensal Bacteria and Enteric Neurons, via FPR1 Induction of ROS, Increase Gastrointestinal Motility in Mice.

Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8 T-Cell Activation.

TNFα promotes mucosal wound repair through enhanced platelet activating factor receptor signaling in the epithelium.

Innate immune cell-epithelial crosstalk during wound repair.

IFN-γ-tethered hydrogels enhance mesenchymal stem cell-based immunomodulation and promote tissue repair.

Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair.

Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo.

MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State.

Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18.

Integrated Imaging Methodology Detects Claudin-1 Expression in Premalignant Nonpolypoid and Polypoid Colonic Epithelium in Mice.

Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration.

Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration.

Western diet-induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis.

Resolvin E1 is a pro-repair molecule that promotes intestinal epithelial wound healing.

Targeting epithelial expressed Sialyl Lewis glycans improves colonic mucosal wound healing and protects against colitis.

Blocking integrin αβ-mediated CD4 T cell recruitment to the intestine and liver protects mice from western diet-induced non-alcoholic steatohepatitis.

Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo.

Dysregulation of intestinal epithelial CFTR-dependent Cl ion transport and paracellular barrier function drives gastrointestinal symptoms of food-induced anaphylaxis in mice.

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis.

WD40 Repeat Protein 26 Negatively Regulates Formyl Peptide Receptor-1 Mediated Wound Healing in Intestinal Epithelial Cells.

IL-36R signaling integrates innate and adaptive immune-mediated protection against enteropathogenic bacteria.