Guoren Deng

Functional role of DNA mismatch repair gene PMS2 in prostate cancer cells.

Simultaneous detection of CpG methylation and single nucleotide polymorphism by denaturing high performance liquid chromatography.

Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.

BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer.

Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor.

Mucinous carcinomas of the colorectum have distinct molecular genetic characteristics.

The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer.

BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer.

Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer.

CpG island methylation is frequently present in tubulovillous and villous adenomas and correlates with size, site, and villous component.

Aberrant expression of SOX2 upregulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorectum and related lesions.

Tumor histology helps to identify Lynch syndrome among colorectal cancer patients.

Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics.

Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability.

Aberrant expression of carbohydrate antigens in cancer: the role of genetic and epigenetic regulation.

Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.

Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs.

Combined analysis of minimal residual disease at two time points and its value for risk stratification in childhood B-lineage acute lymphoblastic leukemia.

Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia.

Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma.

MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer.

Cytochrome P450 17 (CYP17) is involved in endometrial cancinogenesis through apoptosis and invasion pathways.

MicroRNAs 221/222 and genistein-mediated regulation of ARHI tumor suppressor gene in prostate cancer.

Regulatory Role of mir-203 in Prostate Cancer Progression and Metastasis.

MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer.

MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer.

CASP8AP2 is a promising prognostic indicator in pediatric acute lymphoblastic leukemia.

Curcumin modulates microRNA-203-mediated regulation of the Src-Akt axis in bladder cancer.

Catechol-O-methyltransferase-mediated metabolism of 4-hydroxyestradiol inhibits the growth of human renal cancer cells through the apoptotic pathway.

MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells.

Up-regulation of microRNA-21 correlates with lower kidney cancer survival.

Loss of heterozygosity, aberrant methylation, BRAF mutation and KRAS mutation in colorectal signet ring cell carcinoma.

miRNA-708 control of CD44(+) prostate cancer-initiating cells.

MicroRNA-124a and microRNA-34b/c are frequently methylated in all histological types of colorectal cancer and polyps, and in the adjacent normal mucosa.

Genistein suppresses prostate cancer growth through inhibition of oncogenic microRNA-151.

MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer.

miR-23b represses proto-oncogene Src kinase and functions as methylation-silenced tumor suppressor with diagnostic and prognostic significance in prostate cancer.

miRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications, and AKT pathways.

Inhibition of PTEN gene expression by oncogenic miR-23b-3p in renal cancer.

MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer.

Genistein up-regulates tumor suppressor microRNA-574-3p in prostate cancer.

Hrk mediates 2-methoxyestradiol-induced mitochondrial apoptotic signaling in prostate cancer cells.

MicroRNA-23b functions as a tumor suppressor by regulating Zeb1 in bladder cancer.

MicroRNA-4723 inhibits prostate cancer growth through inactivation of the Abelson family of nonreceptor protein tyrosine kinases.

Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells.

Effect of microRNA-210 on prognosis and response to chemotherapeutic drugs in pediatric acute lymphoblastic leukemia.

Regulation of SRC kinases by microRNA-3607 located in a frequently deleted locus in prostate cancer.

Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men.

DNMT3A mutations and prognostic significance in childhood acute lymphoblastic leukemia.

DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells.

Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205.

Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways.

CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma.

Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer.